Results 61 to 70 of about 5,450,980 (351)

Deformation and stress of concrete cut-off wall of Hongshiyan dammed body at initial stage of water storage

open access: yesYantu gongcheng xuebao, 2021
With regard to the technical and theoretical problems of development and engineering safety guarantee of landslide-dammed lakes, the deformation and stress monitoring technology of concrete cut-off wall of dammed body and its installation method based on
HE Ning 1, 2, HE Bin 1, ZHANG Zong-liang 3, ZHANG Zhong-liu 1, ZHOU Yan-zhang 1, WANG Zhang-chun 1, ZHENG Dong 4
doaj   +1 more source

A mechanism of failure in shear bands [PDF]

open access: yesExtreme Mechanics Letters, 2018
We have carried out dilatant plasticity simulations to investigate the process of failure inside a shear band. The constitutive model accounts for possibly inhomogeneous flow within the band, void rotation and void elongation. We found that the material in the band may soften with no increase in the void volume fraction.
Mohammad E. Torki, Ahmed Amine Benzerga
openaire   +2 more sources

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Influences of height of leakage point on uncoordinated deformation of heightening canals in cold areas

open access: yesYantu gongcheng xuebao, 2020
Due to the periodic changes of water supply and temperature in canals in high cold regions, the canal soils will undergo the "wetting-drying and freeze-thaw" cycles, which will aggravate the uncoordinated deformation of the heightening canals.
GUO Wan-li 1, 2, CAI Zheng-yin 1, 2, WANG Yi 3, HUANG Ying-hao 1, 2, ZHANG Chen 2
doaj   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Experimental study on hydraulic fracture of gravelly soil core

open access: yesYantu gongcheng xuebao, 2018
The hydraulic fracture tests on two kinds of graded gravelly soils are carried out by using the improved triaxial apparatus. For the hydraulic fracture pressures on the gravelly soils, the soil properties and confining pressure are the key influence ...
LING Hua 1, 2, WANG Wei 3, WANG Fang 1, 2, FU Hua 1, 2, HAN Hua-qiang 1, 2
doaj   +1 more source

Metabolic Mechanisms in Heart Failure [PDF]

open access: yesCirculation, 2007
Although neurohumoral antagonism has successfully reduced heart failure morbidity and mortality, the residual disability and death rate remains unacceptably high. Though abnormalities of myocardial metabolism are associated with heart failure, recent data suggest that heart failure may itself promote metabolic changes such as insulin resistance, in ...
Ashrafian, Houman   +2 more
openaire   +4 more sources

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Experimental Studies on Strengthening and Failure Mechanism for the Metal/Silicone Rubber/ Metal Bonding System

open access: yes, 2018
In the present research, we carry out a systematical experimental investigation on the strength, toughness and failure mechanism of the metal/silicone rubber/metal bonding system. For the case of the aluminum alloy cylinder/silicone rubber/aluminum alloy
宋晶如   +5 more
core   +1 more source

Elastoplasticity constitutive model considering loading-induced deformation and creep behavior of coarse granular soils and its application

open access: yesYantu gongcheng xuebao, 2019
The field observations show that the existing widely-used constitutive models tend to underestimate the settlement of dams higher than 200 m. One of the main reasons is the separation of load-induced deformation and creep in such models and the ...
CHEN Sheng-shui 1,2, FU Zhong-zhi 1,2, SHI Bei-xiao 1, YUAN Jing 3
doaj   +1 more source

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