Results 61 to 70 of about 965,338 (266)
Effects of porosity on strength and deformation of rockfill materials
Yantu gongcheng xuebao, 2018 In view of the rockfill materials utilized in a 300 m - grade high earth-rock core rockfill dam to be constructed, large static triaxial tests under different porosities are performed to analyze the influences of porosity on strength and deformation of ...
XU Wei-wei1 , SHI Bei-xiao 2,3, CHEN Sheng-shui 2, LING Hua 2,3
doaj +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Yantu gongcheng xuebao, 2017 According to the landslide characteristics of the slope of the reservoir bank of Longjiang Hydropower Station in Yunnan Province, laboratory tests are conducted to investigate the characteristics of the landslide under the combined effects of rainfall ...
LI Zhuo 1, 2, 3, HE Yong-jun 1, 2, SHENG Jin-bao 1, 2, 3, LI Hong-en 1, 2, LI Zheng 1, 2, YANG Yang 1, 2
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FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Centrifugal model tests on section form of drainage channel of barrier dams
Yantu gongcheng xuebao, 2017 The centrifugal model tests on barrier dams overtopping are carried out based on the grain composition of Tangjiashan landslide dam, and the influence laws on the discharge process, released water and the size of the residual dam section of the drainage ...
ZHAO Tian-long 1,2, CHEN Sheng-shui 2,3, FU Chang-jing 1,2, ZHONG Qi-ming 2,3, HOU Ying-wei 1
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Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Yantu gongcheng xuebao, 2018 The extended finite element method combined in ABAQUS software is used to simulate the propagation of crest cracks of an earth core rockfill dam. For the simplified plane FEM model with initial cracks, the conclusions are obtained as follows: the main ...
JI En-yue 1,2, CHEN Sheng-shui 1,2, FU Zhong-zhi 1,2, ZHU Jun-gao 3
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Discusion on Failure Mechanism of Piping
Chemical Engineering Transactions, 2016 Supposing that the layer is consisted of two ideal elastic spheres with different diameters, the permeability coefficient of the layer can be calculated. After piping taking place and small grains being carried away, the permeability coefficient will change.
Fan Z.C., Sun J.
openaire +2 more sources
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source