Results 101 to 110 of about 1,501,755 (279)

Beyond carbon emissions reductions: Examining the co-benefits of industrial decarbonisation in the United Kingdom

Renewable and Sustainable Energy Transition
Industrial decarbonisation reduces greenhouse gases emissions and also deliver broader economic and social gains. We synthesise co-benefits of decarbonising energy-intensive industries in the United Kingdom by combining a scoping review with evidence ...
Abbas AbdulRafiu, Benjamin K. Sovacool, Marc Hudson, M. Mercedes Maroto-Valer, Clare Howard   +4 more
doaj   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Combined STEREO/RHESSI study of CME acceleration and particle acceleration in solar flares

, 2010
Using the potential of two unprecedented missions, STEREO and RHESSI, we study three well observed fast CMEs that occurred close to the limb together with their associated high energy flare emissions in terms of RHESSI HXR spectra and flux evolution ...
Kontar, E. P., Krucker, S., Temmer, M., Veronig, A. M., Vrsnak, B.   +4 more
core   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Tailored laser pulse chirp to maintain optimum radiation pressure acceleration of ions

, 2018
Ion beams generated with ultra-intense lasers-plasma accelerators hold promises to provide compact and affordable beams of relativistic ions. One of the most efficient acceleration setups was demonstrated to be direct acceleration by the laser's ...
Bulanov, S. S., Mackenroth, F.
core   +1 more source

The accelerated acceleration of the universe

Journal of Cosmology and Astroparticle Physics, 2006
We present a simple mechanism which can mimic dark energy with an equation of state w < -1 as deduced from the supernova data. We imagine that the universe is accelerating under the control of a quintessence field, which is moving up a very gently sloping potential.
Csaki, Csaba, Kaloper, Nemanja, Terning, John   +2 more
openaire   +2 more sources

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

FEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini, Nicolò Antonelli, Gianluca Molla   +2 more
wiley   +1 more source

Business Incubators - Drivers of Innovation in the Entrepreneurial Ecosystem [PDF]

Annals of Dunarea de Jos University. Fascicle I : Economics and Applied Informatics
Business incubators play a key role in developing and supporting the entrepreneurial system as they provide a nurturing environment for start-ups, providing important resources and mentoring needed to turn innovative ideas into successful businesses.
Sabin Murariu, Oana Pricopoaia, Nicoleta Cristache, Tiberius Iustinian Stanciu   +3 more
doaj   +1 more source

Establishment of a coculture system for Porphyromonas gingivalis and head and neck squamous cell carcinoma using spheroid culture and LATS inhibition

FEBS Open Bio, EarlyView.
We established a spheroid coculture system enabling viable Porphyromonas gingivalis–HNSCC interactions under normoxic conditions. Inhibition of LATS1/2 maintains tumor cells in an undifferentiated state, which may promote spheroid growth and create a more permissive environment for bacterial persistence.
Yurika Nakajima, Shogo Okazaki, Muneaki Tamura, Shuichi Sato, Kenichi Imai   +4 more
wiley   +1 more source

DDX3X induces mesenchymal transition of endothelial cells by disrupting BMPR2 signaling

FEBS Open Bio, EarlyView.
Elevated DDX3X expression led to downregulation of BMPR2, a key regulator of endothelial homeostasis and function. Our co‐immunoprecipitation assays further demonstrated a molecular interaction between DDX3X and BMPR2. Notably, DDX3X promoted lysosomal degradation of BMPR2, thereby impairing its downstream signaling and facilitating endothelial‐to ...
Yu Zhang, Jing Wang, De‐Hui Qian, Yang‐Fan Lv, Tian‐Le Cheng, Da‐Peng Wang, Jing Zhang, Ye Fan   +7 more
wiley   +1 more source