Results 101 to 110 of about 409,460 (298)

TMC4 localizes to multiple taste cell types in the mouse taste papillae

FEBS Open Bio, EarlyView.
Transmembrane channel‐like 4 (TMC4), a voltage‐dependent chloride channel, plays a critical role in amiloride‐insensitive salty taste transduction. TMC4 is broadly expressed in all mature taste cell types, suggesting a possible involvement of multiple cell types in this pathway.
Momo Murata, Yoshikazu Saito, Yoichi Kasahara, Wataru Fujii, Takumi Misaka, Tomiko Asakura, Masataka Narukawa   +6 more
wiley   +1 more source

A formulation dataset of poly(lactide-co-glycolide) nanoparticles for small molecule delivery

Scientific Data
Poly(lactide-co-glycolide) (PLGA) nanoparticles are promising drug delivery systems, widely recognized for their ability to overcome various limitations associated with conventional formulations.
Anita Goren, Zeqing Bao, Juan Pablo Martinez Lozano, Christine Allen   +3 more
doaj   +1 more source

Applying Resisted Sprint Protocols for Acceleration Improvement in Team Sports: Evidence from a Systematic Review

Physical Education Theory and Methodology
Background. In team sports, decisive actions such as anticipating opponents’ scheme executions and realizing game objectives depend on the ability to accelerate rapidly and maintain high speeds, often under external resistance and during changes of ...
Pompilio Cusano, Agron Kasa, Arben Kaçurri, Gaetano Altavilla   +3 more
doaj   +1 more source

SIRT4 positively regulates autophagy via ULK1, but independently of HDAC6 and OPA1

FEBS Open Bio, EarlyView.
Cells expressing SIRT4 (H161Y), a catalytically inactive mutant of the sirtuin SIRT4, fail to upregulate LC3B‐II and exhibit a reduced autophagic flux under stress conditions. Interestingly, SIRT4(H161Y) promotes phosphorylation of ULK1 at S638 and S758 that are associated with inhibition of autophagy initiation.
Isabell Lehmkuhl, Khawar Amin, Lydia Gabriel, Nils Hampel, Afshin Iram, Julia Hesse, Constanze Wiek, Jasmin Thuy Vy Nguyen, Helmut Hanenberg, Jürgen Scheller, M. Reza Ahmadian, Björn Stork, Doreen M. Floss, Roland P. Piekorz   +13 more
wiley   +1 more source

Author Correction: Cytotoxicity, mutagenicity and genotoxicity of electronic cigarettes emission aerosols compared to cigarette smoke: the REPLICA project

Scientific Reports
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
Rosalia Emma, Virginia Fuochi, Alfio Distefano, Konstantinos Partsinevelos, Sonja Rust, Fahad Zadjali, Mohammed Al Tobi, Razan Zadjali, Zaina Alharthi, Roberta Pulvirenti, Pio Maria Furneri, Riccardo Polosa, Ang Sun, Massimo Caruso, Giovanni Li Volti, the Replica Project Group   +15 more
doaj   +1 more source

Peak match sprinting speed during soccer matches: analysing the pre- and post-peak speed dynamics

Biology of Sport
This study aimed to characterize match peak speeds, during a 20-second time window (10 seconds immediately before and after the match peak speed), in soccer matches. Twenty elite soccer players were monitored with global navigation satellite system (GNSS)
Hugo Silva, Fábio Yuzo Nakamura, Ghazi Racil, Antonio Gómez-Diaz, Pedro Menezes, Karim Chamari, Rui Marcelino   +6 more
doaj   +1 more source

Is there an acceleration of the CpG transition rate during the mammalian radiation? [PDF]

, 2008
Martin Peifer, John Karro, H. H. von Grünberg   +2 more
openalex   +1 more source

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

FEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid, Rapasviranda Soiyangsuk, Maneeluck Tanadjindarat, Chayanon Peerapittayamongkol   +3 more
wiley   +1 more source

Ion Acceleration - Target Normal Sheath Acceleration

, 2016
Energetic ions have been observed since the very first laser-plasma experiments.Their origin was found to be the charge separation of electrons heated by thelaser, which transfers energy to the ions accelerated in the field. The adventof ultra-intense lasers with pulse lengths in the femtosecond regime resulted inthe discovery of very energetic ions ...
Roth, M., Schollmeier, M.
openaire   +2 more sources

Research on Three-Axis Vibration Characteristics and Vehicle Axle Shape Identification of Cement Pavement Under Heavy Vehicle Loads Based on EMD–Energy Decoupling Method

Sensors
The structural integrity of cement concrete pavements, paramount for ensuring traffic safety and operational efficiency, faces mounting challenges from the escalating burden of heavy-duty vehicular traffic.
Pengpeng Li, Linbing Wang, Songli Yang, Zhoujing Ye   +3 more
doaj   +1 more source