Results 71 to 80 of about 395,934 (297)

Multidimensional OMICs reveal ARID1A orchestrated control of DNA damage, splicing, and cell cycle in normal‐like and malignant urothelial cells

open access: yesMolecular Oncology, EarlyView.
Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser   +11 more
wiley   +1 more source

Intersection of Immunity, Metabolism, and Muscle Regeneration in an Autoimmune‐Prone MRL Mouse Model

open access: yesAdvanced Science
Due to the limited capacity of mammals to regenerate complex tissues, researchers have worked to understand the mechanisms of tissue regeneration in organisms that maintain that capacity.
Tran B. Ngo   +6 more
doaj   +1 more source

Chemoresistome mapping in individual breast cancer patients unravels diversity in dynamic transcriptional adaptation

open access: yesMolecular Oncology, EarlyView.
This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani   +14 more
wiley   +1 more source

Inertial Measurement Unit Based Hip Flexion Strength-Power Test for Sprinters

open access: yesFrontiers in Sports and Active Living, 2020
This study aimed to examine whether a recently developed inertial measurement unit (IMU)-based hip flexion strength-power test could be an indicator of sprint performance, step length (SL) and frequency (SF) during sprinting using sprinters. Sixteen well-
Ryu Nagahara, Munenori Murata
doaj   +1 more source

THE ACCELERATING UNIVERSE [PDF]

open access: yes, 2011
In this article we review the discovery of the accelerating universe using type Ia supernovae. We then outline ways in which dark energy - component that causes the acceleration - is phenomenologically described. We finally describe principal cosmological techniques to measure large-scale properties of dark energy.
openaire   +2 more sources

Comprehensive omics‐based classification system in adult patients with B‐cell acute lymphoblastic leukemia

open access: yesMolecular Oncology, EarlyView.
The COMBAT classification system, developed through multi‐omics integration, stratifies adult patients with B‐cell acute lymphoblastic leukemia(B‐ALL) into three molecular subtypes with distinct surface antigen patterns, immune landscape, methylation patterns, biological pathways and prognosis.
Yang Song   +11 more
wiley   +1 more source

Dose‐dependent induction of epithelial‐mesenchymal transition in 3D melanoma models by non‐thermal plasma treatment

open access: yesMolecular Oncology, EarlyView.
Non‐thermal plasma treatment of melanoma cells induced epithelial‐mesenchymal transition (EMT) in a dose‐dependent fashion. This report highlights the critical need to further investigate potential adverse effects of non‐thermal plasma for cancer therapy and to optimize treatment parameters for clinical translation. Despite the promising results of non‐
Eline Biscop   +10 more
wiley   +1 more source

Trailblazers in STEM: a document analysis of the accomplishments of Louis Stokes Alliances for Minority Participation alumni

open access: yesFrontiers in Education
The National Science Foundation (NSF) Louis Stokes Alliance for Minority Participation (LSAMP) has a > 30-year history of providing high impact educational experiences to undergraduates and graduate students of color in science, technology ...
Dominique Smart Graham   +6 more
doaj   +1 more source

Accelerator Modeling with MATLAB Accelerator Toolbox [PDF]

open access: yesPACS2001. Proceedings of the 2001 Particle Accelerator Conference (Cat. No.01CH37268), 2002
This paper introduces Accelerator Toolbox (AT) - a collection of tools to model storage rings and beam transport lines in the MATLAB environment. The objective is to illustrate the flexibility and efficiency of the AT-MATLAB framework. The paper discusses three examples of problems that are analyzed frequently in connection with ring-based synchrotron ...
openaire   +2 more sources

Home - About - Disclaimer - Privacy