Results 61 to 70 of about 264,692 (309)
Molecular Oncology, EarlyView.The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source
Shock and Vibration, 2020 Floating shock platform is generally used to test the antishock performance of large shipboard equipment. Shock acceleration signal will produce zero-shift phenomenon in the test measurement process, which will affect the subsequent shock response ...
Xiongliang Yao +4 more
doaj +1 more source
Ground motion of the Ms7.0 Jiuzhaigou earthquake
Open Geosciences, 2021 Eighty-eight free-field strong ground motion observation datasets obtained by the National Strong Motion Observation Network System of China for the Jiuzhaigou Ms7.0 earthquake were used to study the characteristics of the strong ground motion and the ...
Wang Wencai +8 more
doaj +1 more source
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Response Spectrum Analysis of the Domestic Piston of Reciprocating Compressor Based on ANSYS
Shiyou jixie, 2017 To evaluate the working performance of the domestic piston on reciprocating compressor, taking the crankshaft connecting-rod movement to the dead point as study object, analyses on the modal and response spectrum of the piston and piston rod have been ...
Duan Lixiang +4 more
doaj
Preliminary results of ground-motion characteristics
Annals of Geophysics, 2012 The preliminary results are presented herein for the engineering applications of the characteristics of the ground motion induced by the May 20, 2012, Emilia earthquake.
Francesca Bozzoni +2 more
doaj +1 more source
Shaking Table Tests for Seismic Response of Oblique Overlapped Tunnel
Shock and Vibration, 2021 To study the dynamic response and spectrum characteristics of the three-dimensional crossing tunnel under the action of seismic load, we established a 1/50 downscale model based on a typical of the oblique overlapped tunnel and conducted a series of ...
Hao Lei, Honggang Wu, Tianwen Lai
doaj +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Analyses of strong motion earthquake accelerograms, Volume III - Response spectra; Part U - Accelerograms IIU294 through IIU313 [PDF]
, 1975 This is one of a series of reports presenting earthquake response spectrum curves calculated from corrected accelerograms. In the preface to the first part, Volume III, Part A, Report No.
Earthquake Engineering Research Laboratory,
core