Results 41 to 50 of about 253,667 (293)

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Constructing automatic work analysis system for order picking process

open access: yesJournal of Advanced Mechanical Design, Systems, and Manufacturing, 2022
Work analysis is one of critical tools for improving order picking efficiency in logistics centers. Traditionally, video analysis has been used to analyze work time for various tasks.
Jinyu ZHANG   +3 more
doaj   +1 more source

Instrument for measuring the dynamic behavior of liquids Patent [PDF]

open access: yes, 1969
Pressure sensor network for measuring liquid dynamic response in flight including fuel tank acceleration, liquid slosh amplitude, and fuel depth ...
Powell, C. A., Jr., Stephens, D. G.
core   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Gait Analysis Using Walking-Generated Acceleration Obtained from Two Sensors Attached to the Lower Legs

open access: yesSensors
Gait evaluation approaches using small, lightweight inertial sensors have recently been developed, offering improvements in terms of both portability and usability.
Ayuko Saito   +5 more
doaj   +1 more source

Six-Degree-of-Freedom Sensor Fish Design and Instrumentation

open access: yesSensors, 2007
Fish passing through dams may be injured or killed despite advances in turbinedesign, project operations and other fish bypass systems. The six-degree-of-freedom (6DOF)Sensor Fish device is an autonomous sensor package that characterizes the physical ...
Marshall C. Richmond   +3 more
doaj   +1 more source

Comparing clothing-mounted sensors with wearable sensors for movement analysis and activity classification [PDF]

open access: yes, 2019
Inertial sensors are a useful instrument for long term monitoring in healthcare. In many cases, inertial sensor devices can be worn as an accessory or integrated into smart textiles.
Faustina Hwang   +4 more
core   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Assessment of daily physical activities with sensors attached to the upper limbs in healthy adults using a manual wheelchair

open access: yesJournal of Physical Fitness and Sports Medicine, 2018
This study examined the energy expenditure (EE) of healthy adults during typical use of a manual wheelchair by attaching sensors to the subjects’ upper limbs.
Ryuji Takigawa   +4 more
doaj   +1 more source

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