Results 121 to 130 of about 649,011 (340)

Development of an automated system for the operation of an electron beam accelerator

open access: yesBrazilian Journal of Radiation Sciences, 2019
Electron beam accelerators are used in many applications, such as basic physical research, chemistry, medicine, molecular biology, microelectronics, agriculture and industry, among others.
Samir Luiz Somessari
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

ACCELERATORS FOR STARTUPS IN EUROPE

open access: yesCopernican Journal of Finance & Accounting, 2018
According to Steve Blank, a startup is a temporary organization that is looking for a profitable, scalable, and repeatable business model. The aim of this article is to compare the startup environments in Poland and other European Union countries, in ...
Anna Serwatka
doaj   +3 more sources

Business-catalysts as Drivers of Regional Innovation Systems

open access: yesForesight and STI Governance, 2015
The need to address the tremendous technological and investment risks intrinsic to the stages of business structuring and drawing up a business model means that an optimal tool to support innovative start-ups is sought.
Sergey Makarov, Ekaterina Ugnich
doaj   +1 more source

Linear Accelerators

open access: yes, 2013
35 pages, contribution to the CAS - CERN Accelerator School: Advanced Accelerator Physics Course, Trondheim, Norway, 18-29 Aug 2013.
openaire   +3 more sources

Collimators

open access: yes, 2013
The collimator system of a particle accelerator must efficiently remove stray particles and provide protection against uncontrolled losses. In this article, the basic design concepts of collimators and some realizations are presented.Comment: 5 pages ...
Wronka, Slawomir
core   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

Accelergy: An Architecture-Level Energy Estimation Methodology for Accelerator Designs

open access: yes2019 IEEE/ACM International Conference on Computer-Aided Design (ICCAD), 2019
With Moore's law slowing down and Dennard scaling ended, energy-efficient domain-specific accelerators, such as deep neural network (DNN) processors for machine learning and programmable network switches for cloud applications, have become a promising ...
Yannan Nellie Wu, J. Emer, V. Sze
semanticscholar   +1 more source

Auxiliary propulsion thruster performance with ion machined accelerator grids [PDF]

open access: yes
A substantial improvement in the performance of an 8-centimeter-diameter auxiliary propulsion thruster was achieved by reducing the diameter of the accelerator grid apertures.
Hudson, W. R.
core   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

open access: yesMolecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu   +10 more
wiley   +1 more source

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