Results 111 to 120 of about 350,213 (359)
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
FEBS Letters, EarlyView.Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
Accelerator virtualization [PDF]
Concurrency and Computation: Practice and Experience, 2021 Carlos Reaño +2 more
openaire +2 more sources
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
A template-based design methodology for graph-parallel hardware accelerators [PDF]
, 2017 Graph applications have been gaining importance in the last decade due to emerging big data analytics problems such as Web graphs, social networks, and biological networks.
Burns, S. +5 more
core +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
European Physical Journal C: Particles and Fields, 2018 We present GKG18-DPDFs, a next-to-leading order (NLO) QCD analysis of diffractive parton distribution functions (diffractive PDFs) and their uncertainties. This is the first global set of diffractive PDFs determined within the xFitter framework.
Muhammad Goharipour +2 more
doaj +1 more source
TANGRAM: Optimized Coarse-Grained Dataflow for Scalable NN Accelerators
International Conference on Architectural Support for Programming Languages and Operating Systems, 2019 The use of increasingly larger and more complex neural networks (NNs) makes it critical to scale the capabilities and efficiency of NN accelerators. Tiled architectures provide an intuitive scaling solution that supports both coarse-grained parallelism ...
Mingyu Gao +4 more
semanticscholar +1 more source
Accelerators and Their Ghosts [PDF]
, 2017 Proceedings of the 8th Int.
Rescic, M. +2 more
openaire +1 more source
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Brief Introduction to Particle Accelerators
, 2017 This lecture is a brief introduction to charged particle accelerators. The aim is to provide the reader with basic concepts and tools needed to describe the motion of charged particles under the action of guiding and focussing fields, with an emphasis on
Tavares, P. F.,, Lund University.
core