Results 111 to 120 of about 147,354 (313)

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Accelerating the prevention of HIV and violence in adolescent girls and young women in Zimbabwe through multi-sectoral programming: Cross-sectional analysis of the 2017 violence against children survey

Global Public Health
In Zimbabwe, adolescent girls and young women (AGYW) encounter significant challenges, including HIV risk and gender-based violence. This study analyses data from 7,211 AGYW aged 13–24 from the 2017 Zimbabwe Violence Against Children Survey.
Martina Mchenga, Brendan Maughan-Brown, Rachel Yates, Lucas Hertzog, Boladé Hamed Banougnin, Silinganisiwe Dzumbunu, Madison T. Little, Lucie Cluver, Elona Toska   +8 more
doaj   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

The Largest Accelerators and Colliders of Their Time: LHC

, 2013
This document is part of Subvolume C 'Accelerators and Colliders' of Volume 21 'Elementary Particles' of Landolt-Börnstein - Group I 'Elementary Particles, Nuclei and Atoms'.
R. Bailey, Bailey, R
core   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

Industrial accelerators and their applications

, 2012
This unique new book is a comprehensive review of the many current industrial applications of particle accelerators, written by experts in each of these fields.
Hamm, Marianne E, Hamm, Robert W
core   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

Graph analytics accelerators for cognitive systems [PDF]

, 2017
Hardware accelerators are known to be performance and power efficient. This article focuses on accelerator design for graph analytics applications, which are commonly used kernels for cognitive systems. The authors propose a templatized architecture that
Burns, S., Ozdal, M. M., Ayupov, A., Taemin Kim, Serif Yesil, Kim, T., Steven Burns, Ozcan Ozturk, Andrey Ayupov, Greth, J., Ozturk, O., Yesil, S., Muhammet Mustafa Ozdal, John Greth   +13 more
core   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

The Inflation Accelerator

SSRN Electronic Journal
We develop a tractable sticky price model in which the fraction of price changesevolves endogenously over time and, consistent with the evidence, increases with inflation. Because we assume that firms sell multiple products and choose how many, but not which, prices to adjust in any given period, our model admits exact aggregation and reduces to a one ...
Blanco, Andrés, Boar, Corina, Jones, Callum, Midrigan, Virgiliu   +3 more
openaire   +2 more sources