Results 131 to 140 of about 350,213 (359)
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Molecular Oncology, EarlyView.Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source
Accelerators for high-energy physics
, 2005 The basic principles of linear accelerators, synchrotrons and storage rings, and of their main components are outlined. After a discussion of the performance and key components of hadron colliders, linear electron-positron colliders, and accelerator ...
Hübner, K
core +1 more source
INSTRUMENTAL CAPACITY OF INTERNATIONAL BUSINESS IN MODERN CONDITIONS
Baltic Journal of Economic StudiesThe present study examines the institutional and instrumental capacity of international business in modern conditions. The purpose of the research is to identify and highlight the key institutional capabilities of the modern economy and the tools that ...
Georgii Logvynskyi
doaj +1 more source
Probing the Top Quark Flavour-Changing Neutral Current at a Future Electron-Positron Collider
Advances in High Energy Physics, 2014 We present a study to examine the sensitivity of a future e-e+ collider to the anomalous top flavour-changing neutral current (FCNC) to the gluon. To separate signal from background a multivariate analysis is performed on top quark pair and background ...
Hoda Hesari +3 more
doaj +1 more source
Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
Power converters for cycling accelerators
, 2006 Cycling accelerators require power converters which are capable of storing the energy which oscillates between lattice magnets and converter during the acceleration process.
Marks, N
core +1 more source
Molecular Oncology, EarlyView.We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Accelerators for high energy physics research [PDF]
, 1995 A brief survey of particle accelerators as research tools for high energy physics is given.
Chao, A, Chao, A.
core