Results 151 to 160 of about 350,213 (359)
Molecular Oncology, EarlyView.BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi +11 more
wiley +1 more source
Highly uniform silicon nanopatterning with deep-ultraviolet femtosecond pulses
NanophotonicsThe prospect of employing nanophotonic methods for controlling photon–electron interactions has ignited substantial interest within the particle accelerator community.
Granados Eduardo +4 more
doaj +1 more source
Stimulated Raman backscattering from a laser wakefield accelerator
New Journal of Physics, 2018 Experiments were performed using the HERCULES laser system at the University of Michigan to study backward stimulated Raman scattering (BSRS) from a laser wakefield accelerator driven with a 30 fs pulse.
A E Hussein +11 more
doaj +1 more source
FEBS Open Bio, EarlyView.Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source
Introduction to Plasma Accelerators: the Basics
, 2016 In this article, we concentrate on the basic physics of relativistic plasma wave accelerators. The generation of relativistic plasma waves by intense lasers or electron beams in low-density plasmas is important in the quest for producing ultra-high ...
Trines R +3 more
core +1 more source
FEBS Open Bio, EarlyView.Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda +12 more
wiley +1 more source
Superconducting Magnets for Accelerators
, 2019 Superconducting magnets have enabled great progress and multiple fundamental discoveries in the field of high-energy physics. This chapter reviews the use of superconducting magnets in particle accelerators, introduces Nb$_{3}$Sn superconducting ...
Schoerling, Daniel, Zlobin, Alexander V
core +1 more source
Electron cloud effects in accelerators
, 2020 This article presents a brief overview of the electron-cloud problem in charged-particle accelerators. It covers first and historical observations, simulation efforts, past challenges, modelling achievements, recent successes, objectives and future ...
Zimmermann, F, Zimmermann, F.
core +1 more source
FEBS Open Bio, EarlyView.This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill +4 more
wiley +1 more source
Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system
FEBS Open Bio, EarlyView.An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková +3 more
wiley +1 more source