Results 141 to 150 of about 350,213 (359)
Industrial accelerators and their applications
, 2012 This unique new book is a comprehensive review of the many current industrial applications of particle accelerators, written by experts in each of these fields.
Hamm, Marianne E, Hamm, Robert W
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Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
Electrostatic accelerators: fundamentals and applications
, 2005 Electrostatic accelerators are an important and widespread subgroup within the broad spectrum of modern, large particle acceleration devices. They are specifically designed for applications that require high-quality ion beams in terms of energy stability
Hellborg, Ragnar
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Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
MoleculesGlobal challenges in agriculture, in terms of water and nutrient loss control, require new approaches to maintaining or even increasing crop production. Promising materials, such as superabsorbent hydrogels of hybrid types obtained from natural polymers ...
Elena Manaila +3 more
doaj +1 more source
Molecular Oncology, EarlyView.Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim +3 more
wiley +1 more source
Protocol Techniques for Testing Radiotherapy Accelerators
, 2008 . The nature of radiotherapy accelerators is briefly explained. It is argued that these complex safety-critical systems need a systematic basis for testing their software.
Testing Radiotherapy +5 more
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Ion sources for high-power hadron accelerators
, 2013 Ion sources are a critical component of all particle accelerators. They create the initial beam that is accelerated by the rest of the machine. This paper will introduce the many methods of creating a beam for high-power hadron accelerators.
Faircloth, Dan
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Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source