Results 201 to 210 of about 350,213 (359)

CSF Monoamine Metabolites and Cognitive Trajectory in Early Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Imaging and postmortem studies indicate that abnormalities in monoaminergic neurotransmission contribute to cognitive impairment in Parkinson's disease (PD). However, it remains uncertain if cerebrospinal fluid (CSF) monoamine metabolites can serve as biomarkers of cognitive decline in early PD.
Jing‐Yu Shao, Rong Li, Yu‐Xiang Jiao, Kai Ma, Hong‐Qi Yang, Zheng‐Yu Sun, Jie‐Wen Zhang, Shuai Chen   +7 more
wiley   +1 more source

Applications of Particle Accelerators

Of the tens of thousands of particle accelerators in operation worldwide, the vast majority are not used for particle physics, but instead for applications. Some applications such as radiotherapy for cancer treatment are well-known, while others are more
Sheehy, Suzie
core  

Integrated photonic 3D tensor processing engine. [PDF]

Light Sci Appl
Wu Y, Ni Z, Li X, Wang Y, Lu L, Chen J, Zhou L.   +6 more
europepmc   +1 more source

Elevated Connectivity During Language Processing Is Associated With Cognitive Performance in SeLECTS

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Self‐Limited Epilepsy with Centrotemporal Spikes (SeLECTS) is associated with language impairments despite seizures originating in the motor cortex, suggesting aberrant cross‐network interactions. Here we tested whether functional connectivity in SeLECTS during language tasks predicts language performance.
Wendy Qi, Katharine Lee, Kerry C. Nix, Miguel Menchaca, Xiwei Shé, Lorelei Santa Maria, Wei Wu, Zihuai He, Fiona M. Baumer   +8 more
wiley   +1 more source

Development and validation of a novel pulse optimization and beam control system for conventional and ultra high dose-per-pulse (FLASH) irradiation. [PDF]

Med Phys
Connell L, Esplen N, Lim R, Baikalov A, Coupey N, Nguyen C, Schüler E.   +6 more
europepmc   +1 more source

IV Thrombolysis Facilitates Interventional Reperfusion in Non‐Cardioembolic but Not Cardioembolic Stroke

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Intravenous thrombolysis (IVT) before thrombectomy for ischemic stroke may alter clot structure and procedural performance. We investigated how IVT relates to thrombectomy metrics across stroke etiologies. Methods We performed a time‐to‐event analysis of consecutive patients with anterior circulation large vessel occlusion (acLVO ...
Annahita Sedghi, Daniel P. O. Kaiser, Martin Arndt, Norma J. Diel, Erik Simon, Witold H. Polanski, Volker Puetz, Hagen B. Huttner, Timo Siepmann   +8 more
wiley   +1 more source

Multi-Charged Ion Sources for Pulsed Accelerators

, 1995
The relatively low duty cycle of pulsed accelerators can give rise to problems in matching the characteristics of multi-charged ion sources to the beam intensity required by the user.
Hill, C E, Haseroth, H
core  

Microleakage in 5Y-TZP zirconia ceramic crowns and the influence of deep margin elevation: a laboratory investigation. [PDF]

Clin Oral Investig
Jansen L, Kern M, Wille S, Schadte P, Passia N.   +4 more
europepmc   +1 more source

ALDOA Promotes Glycolysis and NLRP3/GSDMD Pyroptosis to Accelerate ALS Progression

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is characterized by progressive motor neuron degeneration. Glycolytic dysregulation is implicated in disease progression, yet the underlying mechanisms remain unclear. This study investigates how Aldolase A (ALDOA) drives ALS progression through glycolysis‐mediated motor neuron pyroptosis.
Kaixin Yan, Yan Jiang, Yuxuan Yong, Tianshuo Zhang, Niannian Zhang, Qianqian Zeng, Xue Gong, Li Meng, Fangfang Bi, Yongmin Liu   +9 more
wiley   +1 more source

Future accelerators

, 1998
An overview of the various schemes for electron-positron linear colliders is given and the status of the development of key components and the various test facilities is given.
Hübner, K
core