Results 121 to 130 of about 58,510 (335)
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
The Accent of Masculine O-Stems in the Dialect of Komazini
Rasprave Instituta za Hrvatski Jezik i Jezikoslovlje, 2013 Neo-Štokavian dialects preserve the inherited Proto-Slavic accent paradigms relatively well. The paper discusses the accentuation of the masculine o-stems in the Neo-Štokavian dialect of Komazini and describes the changes that occurred in the accent ...
Perina Vukša Nahod
doaj
Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
The Unattainable Standard — Zagreb Dialect Meets Standard Croatian Accentuation
Slovene, 2018 The paper discusses the accentual accommodation by speakers of the urban dialect of Zagreb (the capital of Croatia), which has a dynamic free accent, to the Standard Croatian (Neo-Štokavian) pitch accent (with rising and falling tones). The accommodation
Mate Kapović
doaj
From Local to Global Analysis of Music Time Series [PDF]
Local and more and more global musical structure is analyzed from audio time series by time-series-event analysis with the aim of automatic sheet music production and comparison of singers. Note events are determined and classified based on local spectra,
Ligges, Uwe, Weihs, Claus
core
E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer
Molecular Oncology, EarlyView.Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov +3 more
wiley +1 more source
On the Accentuation of neslъ and Related Issues
Rasprave Instituta za Hrvatski Jezik i Jezikoslovlje, 2014 In a recent article of major importance (2013), Tijmen Pronk has treated the accentuation of l-participles of the type neslъ in western South Slavic. Pronk points out correctly that Dybo’s law did not shift the accent onto final jers, e.g.
Frederik Kortlandt
doaj
Accentuation of i-verbs in the Sixteenth-century Chronograph from the E. V. Barsov Collection
, 2018 Anastasia K. Polivanova
openalex +1 more source
Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics
FEBS Open Bio, EarlyView.Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini +2 more
wiley +1 more source