Results 101 to 110 of about 3,458,846 (288)
Navigating toward acceptance of death: Home-dwelling patients in the palliative phase
Background As global life expectancy increases, the need for palliative care grows. Recognizing the deeply personal and diverse nature of individuals’ end-of-life experiences, palliative care for home-dwelling patients requires a flexible and person ...
Katrine Staats +2 more
doaj +1 more source
Background: Food management is inseparable part of all efforts to cure hospitalized patients. If patient is not able to consume enough food, nutrient deficiency will occur.
Dewi Renaningtyas +2 more
doaj +1 more source
Structural biology of ferritin nanocages
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Scene 1 An office with “Headmaster” written on the main desk, and several chairs on either side. A man walks towards the desk and starts looking over some papers. He picks up the telephone. Headmaster: Francis, could you please ask Andrew to check if the school site is functioning properly? This last print-out still has Mr Hind as part of the staff,
openaire +2 more sources
Three recent papers underline the importance of the host genomic background in allowing the stable maintenance of horizontally acquired genes. These studies suggest that post-transfer changes in both host genome and acquired genes contribute to the stable integration of foreign genes.
openaire +3 more sources
Determinants of Food Acceptance and Micro-Nutrient Deficiency in Preschoolers: A Case Study of Households from Karachi, Pakistan [PDF]
This study attempts to find out the determinants of food acceptance and micro-nutrient deficiency in preschool children from Karachi, Pakistan. Primary data was collected through survey from 400 households by interviewing and filling up the questionnaire.
Ali, Muhammad +2 more
core +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
The coronavirus disease (COVID-19) is one of the largest public health threats in recent times, with significant health, economic, and social consequences globally.
Chikezie Ifeanyi +16 more
doaj +1 more source

