Results 91 to 100 of about 1,492,720 (294)

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

FEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança, Eline L. Jansen, Jorine M. Eeftens   +2 more
wiley   +1 more source

Physicians’ attitudes and acceptance towards artificial intelligence in medical care: a qualitative study in Germany

Frontiers in Digital Health
BackgroundThe role of artificial intelligence (AI) in medicine is rapidly expanding, with the potential to transform physicians’ working practices across various areas of medical care.
Sarah Negash, Jana Gundlack, Charlotte Buch, Timo Apfelbacher, Jan Schildmann, Thomas Frese, Jan Christoph, Jan Christoph, Rafael Mikolajczyk   +8 more
doaj   +1 more source

Translophagy—A potential link between autophagy impairment and translational errors

FEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk, Gailing Ma, Robin Antrobus, Diego Manni, Marco Trevisan‐Herraz, Mustafa Khwaja, Max Brown, Gavin D. Richardson, Masaaki Komatsu, Daniel Erskine, Viktor I. Korolchuk, Tetsushi Kataura   +11 more
wiley   +1 more source

Facettes de l'exil dans la diaspora féminine roumaine contemporaine

ACROSS
The transformation of self in connection with space highlights a heightened sensitivity to the external world in relation to human identity. This interdependence, in which the geographical boundaries impose themselves as essential conditions for ...
Iulia ROMAN
doaj   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

FEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell, Thomas Walther, Egbert Hoiczyk   +2 more
wiley   +1 more source

Coronavirus Disease 2019 Vaccine Hesitancy and Acceptance among the Indian Population: A Systematic Review and Meta-analysis

Journal of Global Infectious Diseases
Introduction: The disastrous impact of the coronavirus disease 2019 (COVID-19) pandemic worldwide necessitated the prompt development of vaccines to combat the situation; however, vaccination drives have been challenged by vaccine hesitancy among several
Janmejaya Samal, G. S. Preetha, R. Praveen Kumar, Neha Lakshman, Ranjit Kumar Dehury, Hari Singh   +5 more
doaj   +1 more source

“It Was Very Comforting to Find Out Right Away.” – Patient Perspectives on Point-of-Care Molecular SARS-CoV-2 Testing in Primary Care

Patient Preference and Adherence, 2022
Anni Matthes,1,2 Florian Wolf,1 Jutta Bleidorn,1 Robby Markwart1,2 1Institute of General Practice and Family Medicine, Jena University Hospital, Friedrich Schiller University, Jena, Thuringia, Germany; 2InfectoGnostics Research Campus Jena, Jena ...
Matthes A, Wolf F, Bleidorn J, Markwart R   +3 more
doaj  

Structural and biochemical analysis of a B12 superbinder

FEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices, Jacob J. Whittaker, Dirk J. Slotboom, Albert Guskov   +3 more
wiley   +1 more source

Eat prey and love: Game‐meat consumption and attitudes toward hunting

Wildlife Society Bulletin, 2012
Public support of hunting is a key to sustaining this socio‐economic activity that contributes to control of game populations. Previous studies have suggested that experience with hunting and hunters may determine acceptance of hunting.
Per E. Ljung, Shawn J. Riley, Thomas A. Heberlein, Göran Ericsson   +3 more
doaj   +1 more source

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

FEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav, Bogdan I. Florea, Sebastian Geibel   +2 more
wiley   +1 more source