Results 101 to 110 of about 1,445,341 (287)
FEBS Letters, EarlyView.Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
‘Guide and Prejudice’— How Argonautes recognize targets across domains of life
FEBS Letters, EarlyView.Argonaute proteins use short nucleic‐acid guides to locate and regulate specific targets across all domains of life. Despite striking diversity—from human gene silencing to bacterial immune defence—all Argonautes share a conserved three‐stage recognition logic: guide‐directed sampling, progressive target pairing with a conformational checkpoint and ...
Jack P. K. Bravo
wiley +1 more source
Aspects of acceptance: building a shared conceptual understanding
Frontiers in PsychologyMany contemplatives, scientists, and clinicians have pointed to the value of responding to life’s difficulties by accepting experiences as they are. A growing body of research also suggests that acceptance contributes to effective coping with adversity ...
Michael D. Mrazek +8 more
doaj +1 more source
International Journal of General Medicine, 2023 Chailat Maluangnon,1 Paweena Kanogpotjananont,1,2 Surat Tongyoo1 1Department of Medicine, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand; 2Department of Medicine, Chaopraya Abhaiphubejhr Hospital, Prachinburi ...
Maluangnon C +2 more
doaj
Structural and biochemical analysis of a B12 superbinder
FEBS Letters, EarlyView.BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
FEBS Letters, EarlyView.Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
Multilevel Fixed and Sequential Acceptance Sampling: The R Package MFSAS [PDF]
Multilevel acceptance sampling for attributes is used to decide whether a lot from an incoming shipment or outgoing production is accepted or rejected when the product has multiple levels of product quality or multiple types of (mutually exclusive ...
Aaron Childs, Yalin Chen
core
FEBS Letters, EarlyView.How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
PsychologicaSexual minority (SM) individuals present lower levels of mental health compared to their heterosexual peers. This study aimed to explore the preliminary evidence of a manualized 13-week, face-to-face affirmative group intervention for SM individuals ...
Daniel Seabra +3 more
doaj +1 more source
The effectiveness of acceptance and commitment group therapy on autobiographical memory in non-clinical sample of depressed people [PDF]
روانشناسی و روانپزشکی شناخت, 2017 Overgeneralization in autobiographical memories is one of the cognitive problems that depressed people are facing and cause of persistence and recurrence of depression.
Elham Ghalkhani +4 more
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