Results 61 to 70 of about 809,777 (269)

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Using E-Learning to Deliver In-Service Teacher Training in the Vocational Education Sector: Perception and Acceptance in Poland, Italy and Germany

Education Sciences, 2020
For teachers in vocational education and training (VET), lifelong learning and related further training is important to meet the growing demands of the teaching profession.
Christian Hofmeister, Matthias Pilz
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

An Examination of Whether Mindfulness Can Predict the Relationship Between Objective and Subjective Attitudinal Ambivalence

Frontiers in Psychology, 2019
Ambivalence is a mixed reaction toward an attitudinal object. Ambivalence is often viewed as aversive and people are motivated to reduce it. However, the presence of both strong positive and negative attitudes toward an object (objective ambivalence; OA)
Jennifer Weng, Kenneth G. DeMarree
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Low Tidal Volume Ventilation in Percutaneous Liver Ablations: Preliminary Experience on 10 Patients

Diagnostics
Objectives: Low tidal volume ventilation (LTVV) is a ventilatory strategy with the advantages of minimizing diaphragm movements and reducing hypercapnia and barotrauma risks.
Francesco Giurazza, Francesco Coletta, Antonio Tomasello, Fabio Corvino, Silvio Canciello, Claudio Carrubba, Vincenzo Schettini, Francesca Schettino, Romolo Villani, Raffaella Niola   +9 more
doaj   +1 more source

To accept, or not to accept, that is the question: citizen reactions to rationing [PDF]

Health Expectations, 2011
AbstractBackground  The publicly financed health service in Sweden has come under increasing pressure, forcing policy makers to consider restrictions.Objective  To describe different perceptions of rationing, in particular, what citizens themselves believe influences their acceptance of having to stand aside for others in a public health service.Design 
Broqvist, Mari, Garpenby, Peter
openaire   +3 more sources

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Respiratory Syncytial Virus infection: New prevention strategies

Global Pediatrics
Respiratory Syncytial Virus is the most common respiratory pathogen in infants and young children. Despite its global impact on human health, no effective treatment is available except for supportive therapy. In the last two decades, our understanding of
Anna Chiara Vittucci, Livia Antilici, Andrea Dotta, Renato Cutrera, Alberto Villani   +4 more
doaj   +1 more source