Results 61 to 70 of about 335,545 (298)

Translophagy—A potential link between autophagy impairment and translational errors

FEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk, Gailing Ma, Robin Antrobus, Diego Manni, Marco Trevisan‐Herraz, Mustafa Khwaja, Max Brown, Gavin D. Richardson, Masaaki Komatsu, Daniel Erskine, Viktor I. Korolchuk, Tetsushi Kataura   +11 more
wiley   +1 more source

Accepting test-anxiety-related thoughts increases academic performance among undergraduate students [PDF]

Psihologija, 2012
Given that unwanted thoughts are enhanced when suppressed, we tested among college freshmen who were about to take an academic exam if an acceptance strategy consisting of not suppressing intrusive thoughts will improve test performance. This strategy
Senay Ibrahim, Cetinkaya Mustafa, Usak Muhammet   +2 more
doaj   +1 more source

Structural and biochemical analysis of a B12 superbinder

FEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices, Jacob J. Whittaker, Dirk J. Slotboom, Albert Guskov   +3 more
wiley   +1 more source

Is the KKondae as a common psychological construct? Testing the KKondae scale with the U.S. sample, and the preliminary study of predictors and consequences of Kkondae

BMC Psychology
Background The research aims to explore the common nature of ‘kkondae’—a Korean term denoting stubbornness—and its relevance across cultures, particularly examining the relationship between anxiety, kkondae tendencies, and resulting loneliness through ...
Jiyeon Lee, Dongwoo Ko, Hyoung-yong Choi
doaj   +1 more source

L‐aspartate oxidase provides new insights into fumarate reduction in anaerobic darkness in Synechocystis sp. PCC6803

FEBS Letters, EarlyView.
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil, Jeffrey A. Hawkes, Cecilia Blikstad, Pia Lindberg   +3 more
wiley   +1 more source

Status quo and influencing factors of social alienation in ovarian cancer patients accepting postoperative chemotherapy

Huli yanjiu, 2023
ObjectiveTo understand status quo of social alienation in ovarian cancer patients accepting postoperative chemotherapy and analyze its influencing factors.Methods194 ovarian cancer patients accepting postoperative chemotherapy in gynecology department of
HAO Limin, HAN Wenping, HAN Huiqin, CHAI Peishan   +3 more
doaj  

The Stochastics of Threshold Accepting: Analysis of an Application to the Uniform Design Problem [PDF]

Threshold Accepting (TA) is a powerful optimization heuristic from the class of stochastic local search algorithms. It has been applied successfully to different optimization problems in statistics and econometrics, including the uniform design problem ...
Winker, Peter
core  

Haploidentical Hematopoietic Cell Transplantation for Infants With X‐Linked Severe Combined Immunodeficiency Using Post‐Transplant Cyclophosphamide

Pediatric Blood &Cancer, EarlyView.
Shuhei Takahashi, Akito Kawachi, Dan Tomomasa, Eri Watanabe, Yuji Fujita, Yuya Sato, Masahiro Sekiguchi, Kentaro Watanabe, Moe Hidaka, Akihiro Hoshino, Takahiro Kamiya, Masatoshi Takagi, Hirokazu Kanegane, Motohiro Kato   +13 more
wiley   +1 more source

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

FEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux, Christian Lévêque, Fodil Azzaz, Marion Sangiardi, Sarosh R Irani, Michael Seagar, Jacques Fantini, Oussama El Far   +7 more
wiley   +1 more source

Evaluation of Indicators for Measuring and Accepting Mobile Commerce [PDF]

سیاست نامه علم و فناوری, 2021
With the increasing influence of the media in society, the need to use mobile commerce has become more important than ever. Due to the novelty of this field, the adoption of its use by individuals has faced various challenges.
Ehram Safari, mohammad Kazem Sayadi , leila sarikhani   +2 more
doaj