Results 71 to 80 of about 1,407,660 (301)
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Acceptance of Disability and the Risk of Frailty
Canadian Geriatrics Journal, 2013 Background The objectives are to determine if: 1) accepting disability as a part of aging is associated with frailty; and 2) accepting disability is associated with becoming frail over a five-year period.
Philip D. St. John, Patrick Montgomery
doaj +1 more source
Geobacter, Anaeromyxobacter and Anaerolineae populations are enriched on anodes of root exudate-driven microbial fuel cells in rice field soil [PDF]
, 2015 Plant-based sediment microbial fuel cells (PMFCs) couple the oxidation of root exudates in living rice plants to current production. We analysed the composition of the microbial community on anodes from PMFC with natural rice field soil as substratum for
Arends +33 more
core +1 more source
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
Public Dollars, Private Discrimination: Protecting LGBT Students from School Voucher Discrimination [PDF]
, 2018 More than a dozen states operate school voucher programs, which allow parents to apply state tax dollars to their children’s private school tuition.
Mengler, Adam
core +1 more source
Molecular Oncology, EarlyView.Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
امام ابن تیمیہ کے حدیث کےردوقبول کے معیارات کا تحقیقی مطالعہ
پاکستان جرنل آف اسلامک فلاسفیThe Prophetic traditions (Ahadith) are a fundamental component of Islam, serving as the primary source of Shariah after the Quran. Ensuring the authenticity, reliability and acceptance or rejection of Ahadith has always been a priority for Islamic ...
Muhammad Rizwan
doaj
“Participating means accepting”: debating and contesting synthetic biology
New Genetics and Society, 2017 This article analyses opposition to public debates. In doing so, the article builds upon the tradition of analyzing controversies by symmetrically describing the advocates and the opponents of public debates.
Morgan Meyer
doaj +1 more source
, 2019 Risk-taking in honors education entails not only anxiety about grades and intellectually disturbing ideas but also painful emotional responses to course materials. Rather than censoring such “dangerous” materials, faculty should compassionately encourage
Andrews, Larry R.
core +1 more source