Results 81 to 90 of about 335,545 (298)
“Participating means accepting”: debating and contesting synthetic biology
New Genetics and Society, 2017 This article analyses opposition to public debates. In doing so, the article builds upon the tradition of analyzing controversies by symmetrically describing the advocates and the opponents of public debates.
Morgan Meyer
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Acceptance of Disability and the Risk of Frailty
Canadian Geriatrics Journal, 2013 Background The objectives are to determine if: 1) accepting disability as a part of aging is associated with frailty; and 2) accepting disability is associated with becoming frail over a five-year period.
Philip D. St. John, Patrick Montgomery
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Splicing Systems: Accepting Versus Generating. [PDF]
, 2011 In this paper we propose a condition for rejecting the input word by an accepting splicing system which is defined by a finite set of forbidding words. We investigate the computational power of the new variants of accepting splicing systems. We show that
Mitrana, Víctor +5 more
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Molecular Oncology, EarlyView.This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault +12 more
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, 1969 Photograph used for a story in the Daily Oklahoman newspaper. Caption: "ACCEPTING the Navy Achievement Medal from Capt. Jack Moore, right, is Wilbert D. Wallace, Oklahoma City.
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JOSHUA MEHIGAN, Accepting the Disaster [PDF]
, 2016 Review of Joshua Mehigan's second poetry volume, ACCEPTING THE ...
Dowling, Gregory
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Molecular Oncology, EarlyView.Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu +9 more
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Molecular Oncology, EarlyView.The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim +17 more
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Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation
Molecular Oncology, EarlyView.How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim +11 more
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