Results 211 to 220 of about 4,425,929 (269)

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

IHIBE: A Hierarchical and Delegated Access Control Mechanism for IoT Environments. [PDF]

Sensors (Basel)
Purnama H, Mambo M.
europepmc   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Comparative analysis of identity management, access control, and authorization practices in public and private universities. [PDF]

Open Res Eur
Mollakuqe E, Dimitrova V.
europepmc   +1 more source

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

Molecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski, Júlia Perera‐Bel, Alejo Rodriguez‐Vida, Nuria Juanpere, Jihyun Lee, Daniel E. Michaud, Jennifer L. Guerriero, Kent W. Mouw, Aristotelis Bamias, Filipe L. F. Carvalho, Joaquim Bellmunt   +10 more
wiley   +1 more source

SDACS: Blockchain-Based Secure and Dynamic Access Control Scheme for Internet of Things. [PDF]

Sensors (Basel)
Gong Q, Zhang J, Wei Z, Wang X, Zhang X, Yan X, Liu Y, Dong L.   +7 more
europepmc   +1 more source

PatCen: A blockchain-based patient-centric mechanism for the granular access control of infectious disease-related test records. [PDF]

PLoS One
Yakubu BM, Ali SM, Khan MI, Bhattarakosol P.   +3 more
europepmc   +1 more source

Blockchain-based proxy re-encryption access control method for biological risk privacy protection of agricultural products. [PDF]

Sci Rep
Wang S, Luo N, Xing B, Sun Z, Zhang H, Sun C.   +5 more
europepmc   +1 more source

Blockchain Based Auditable Access Control For Business Processes With Event Driven Policies. [PDF]

IEEE Trans Dependable Secure Comput
Akhtar A, Barati M, Shafiq B, Rana O, Afzal A, Vaidya J, Shamail S.   +6 more
europepmc   +1 more source