Results 141 to 150 of about 94,242,737 (296)

Avidin is evolutionarily conserved in fish but dispensable for development and resistance against Streptococcus agalactiae in zebrafish

open access: yesFEBS Open Bio, EarlyView.
The presence of biotin‐binding avidin proteins in fish and their biological significance are poorly characterized. We cataloged fish avidins and demonstrate that they are widely present and evolutionarily conserved. We created avd knockout zebrafish and show that zebavidin is dispensable for development and that resistance of avd knockout embryos in ...
Anni K. Saralahti   +5 more
wiley   +1 more source

Post-trial access to medication: an approach based on different knowledge

open access: yesO Mundo da Saúde, 2016
This article approaches clinical trials to test medication in Brazil, and its goal is to analize the issue of post-trial access to drugs that have proven to be beneficial to the research participants from the ethical, sanitary, legal and of the human ...
Bruno Rodolfo Schlemper Junior   +1 more
doaj  

Access to Knowledge Treaty

open access: yes, 2005
WIPO is considering an Access to Knowledge Treaty as part of its development agenda. (In case you've forgotten, this is not your father's WIPO. The development agenda has promising implications for OA.) If you have ideas for the treaty, then send them to the a2k (Access to Knowledge) email list or to Jamie Love.
openaire   +1 more source

Comparative assessment of crystallographic and cryo‐EM models in the Protein Data Bank

open access: yesFEBS Open Bio, EarlyView.
Raw data obtained by X‐ray crystallography or cryo‐EM result in experimental maps, ultimately fitted by atomic models. Although the physical principles are different, the final results can be viewed, compared, and evaluated in the same way. With cryogenic electron microscopy (cryo‐EM) on track to surpass X‐ray crystallography as the preferred method ...
Alexander Wlodawer   +7 more
wiley   +1 more source

Structural and biochemical insights into the thermostable esterase Ta0887 from Thermoplasma acidophilum

open access: yesFEBS Open Bio, EarlyView.
In this study, a novel esterase from the thermoacidophilic archaeon Thermoplasma acidophilum was biochemically and structurally characterized. Our results demonstrate that Ta0887 is a highly thermostable esterase that preferentially hydrolyzes p‐nitrophenyl hexanoate and possesses an α‐helical cap domain that likely contributes to its substrate ...
Alejandro Delgado‐Rey   +4 more
wiley   +1 more source

Report of the Privacy Public Records Access Study Committee.

open access: yes, 2007
Title from cover of PDF.; "October 25, 2007."; Includes document referred to on P. 2 and P. 9: Recommendation and Report of the Privacy and Public Access Subcommittee of the Supreme Court of Ohio Advisory Committee on Technology and the Courts on Public ...
Ohio. Privacy Public Records Access Study Committee.
core  

Cell surface CD11c as a neutrophil aging marker molecule

open access: yesFEBS Open Bio, EarlyView.
Cell surface CD11chi neutrophils were more aged and had better phagocytic function than CD11c−/lo neutrophils. Transcriptomic analysis of CD11chi neutrophils and CD11c−/lo neutrophils in pediatric population showed that the most difference was seen in infants.
Sophia Koutsogiannaki   +5 more
wiley   +1 more source

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