Results 151 to 160 of about 7,433,094 (307)

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

FEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin, Ziyang Yuan, Wenli Jiang, Ai Guo   +3 more
wiley   +1 more source

An open access medical knowledge base for community driven diagnostic decision support system development. [PDF]

BMC Med Inform Decis Mak, 2019
Müller L, Gangadharaiah R, Klein SC, Perry J, Bernstein G, Nurkse D, Wailes D, Graham R, El-Kareh R, Mehta S, Vinterbo SA, Aronoff-Spencer E.   +11 more
europepmc   +1 more source

Access to knowledge v. enclosure

, 2005
Pedro de Paranaguá Moniz, The Development Agenda for WIPO: Another Stillbirth? A Battle Between Access to Knowledge and Enclosure, an LLM dissertation at the University of London, approved in July 2005 and self-archived in SSRN on November 14, 2005.
openaire   +1 more source

Sudden anaerobization in Amphibacillus xylanus increases intracellular labile ferrous iron and inhibits cell growth

FEBS Open Bio, EarlyView.
Abruptly changing from aerobic to anaerobic conditions (sudden anaerobization) induced growth inhibition and a significant increase in intracellular labile ferrous iron in the aerotolerant anaerobe Amphibacillus xylanus. We found that free flavins mediate efficient electron transfer from NADH to ferric iron under anaerobic conditions, suggesting that ...
Shinya Kimata, Yoichi Sakai, Keisuke Tanaka, Etsuro Yoshimura, Ken Kitano, Morio Ishikawa, Tadahiro Nakamoto, Tsutomu Takayama, Hirofumi Inoue, Kaho Nomura, Tomonori Suzuki, Masataka Uchino, Akira Abe, Youichi Niimura   +13 more
wiley   +1 more source

Post-trial access to medication: an approach based on different knowledge

O Mundo da Saúde, 2016
This article approaches clinical trials to test medication in Brazil, and its goal is to analize the issue of post-trial access to drugs that have proven to be beneficial to the research participants from the ethical, sanitary, legal and of the human ...
Bruno Rodolfo Schlemper Junior, Aline Albuquerque   +1 more
doaj  

COVID-19 Strategic Global North-South Divide: Access to Knowledge Quadrants Imperatives for Granting the WTO Waiver

, 2021
Ola K.
europepmc   +1 more source

Lipopolysaccharide uptake is augmented in lipopolysaccharide‐tolerant mouse macrophage‐like cells via increased CD14 expression

FEBS Open Bio, EarlyView.
In normal (nontolerant) cells, CD14 is crucial for both LPS uptake and LPS signaling. In LPS‐tolerant cells, in which LPS‐induced TNF‐α and IFN‐β production is suppressed, there is a dramatic increase in surface CD14 expression. The overexpressed CD14 in LPS‐tolerant cells is responsible for the enhanced LPS uptake without inducing pro‐inflammatory ...
Saeka Nishihara, Takayuki Manabe, Mika Jouta, Kiyoshi Kawasaki   +3 more
wiley   +1 more source

SymbioGenomesDB: a database for the integration and access to knowledge on host-symbiont relationships. [PDF]

Database (Oxford), 2015
Reyes-Prieto M, Vargas-Chávez C, Latorre A, Moya A.   +3 more
europepmc   +1 more source

Aging Is a Key Driver for Adult Acute Myeloid Leukemia

Aging and Cancer, EarlyView.
Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley   +1 more source

Cancer's Margins: Trans* and Gender Nonconforming People's Access to Knowledge, Experiences of Cancer Health, and Decision-Making. [PDF]

LGBT Health, 2016
Taylor ET, Bryson MK.
europepmc   +1 more source