Results 71 to 80 of about 1,731,910 (308)

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

open access: yesMolecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak   +10 more
wiley   +1 more source

Public environmental information: understanding requirements and patterns of likely public use

open access: yes, 2002
Public access to environmental information received much attention in the last decade. Recent developments promote access to this information through public telecommunication networks.
Haklay, M
core  

IFLA Guidelines on Public Internet Access in Libraries

open access: yes, 2019
IFLA's Guidelines on Public Internet Access in Libraries offer both a firm reiteration of support for the value of such access, but also practical guidance in dealing with the issues that this may raise.
IFLA Freedom of Access to Information and Freedom of Expression (FAIFE) Advisory Committee
core   +1 more source

ESR1 methylation and ESR1 mutations in circulating tumor cells (CTCs) and paired plasma‐cfDNA of advanced breast cancer patients: A feasibility proof‐of‐concept study

open access: yesMolecular Oncology, EarlyView.
Circulating tumor cells (CTCs) and plasma cell‐free DNA (cfDNA) were analyzed to detect ESR1 mutations and methylation in patients with advanced breast cancer. CTC‐derived DNA showed higher sensitivity for mutation detection and revealed complementary genetic and epigenetic alterations, highlighting the added value of CTC analysis for understanding ...
Dimitra Stergiopoulou   +12 more
wiley   +1 more source

Diversity in universality

open access: yesKnjižnica, 2001
Multiculturalism is one of the principles of library functioning. Each well-operated library tries to realise it by the contents of its collection and by providing access for all potential users.
Silva Novljan
doaj   +1 more source

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

open access: yesMolecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen   +14 more
wiley   +1 more source

Access to public sector information : law, technology and policy

open access: yes, 2010
On the back of the growing capacity of networked digital information technologies to process and visualise large amounts of information in a timely, efficient and user-driven manner we have seen an increasing demand for better access to and re-use of ...
Fitzgerald, Brian F.
core  

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

Right to Information, Information Literacy and Libraries

open access: yes, 2006
Highlights the interdependence of Right to Information (RTI) and information literacy, and the role of public libraries which acts as catalyst between the two.
Raman Nair, R.
core  

Open public sector information: from principles to practice [PDF]

open access: yes, 2013
Accessible information is the lifeblood of a robust democracy and a productive economy. As part of a worldwide movement, the Australian Government is fundamentally changing the way that information is valued, managed, used and shared with others.
John McMillan
core  

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