Fetal Brain Tumor Harboring a Unique ROCK1::BRAF Fusion
Pediatric Blood &Cancer, EarlyView.
Marllon Cindra Sant'Ana +8 more
wiley +1 more source
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Vertical integration and costly demand information in regulated network industries [PDF]
, 2008 We study how vertical integration in regulated network industries affects the acquisition and transmission of socially valuable information on demand. We consider a regulated upstream monopoly with downstream unregulated Cournot competition and demand ...
Iossa, E, Stroffolini, F
core
The case of public transport infrastructure in Malta, and its impact on the elderly [PDF]
, 2016 The concept of equity is essential in transport because inequities lead to the formation of transport-disadvantaged groups, such as the elderly, disabled and low-income people. This paper focuses on the elderly.
Bajada, Therese +2 more
core +1 more source
Molecular Oncology, EarlyView.This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris +10 more
wiley +1 more source
A tangled web of access to information: reflections on R (on the application of Evans) and another v Her Majesty's Attorney General [PDF]
, 2015 The Freedom of Information Act 2000 (‘FOIA’) came into force on 1 January 2005. It created, for the first time, a statutory right of access to information held by a wide range of public authorities.
Mc Cullagh, Karen
core +1 more source
Tumor mutational burden as a determinant of metastatic dissemination patterns
Molecular Oncology, EarlyView.This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal +4 more
wiley +1 more source
Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer
Molecular Oncology, EarlyView.PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta +10 more
wiley +1 more source
Íconos, 2015 The following article analyzes public policies of administrative reform and related to the institutionalization of access to public information in Mexico, Guatemala and Honduras.
Vera Martínez, Martín Cutberto +2 more
doaj +1 more source
Electronic Library Collections and Users with Visual Impairments: Challenges, Developments, and the State of Collections Policies in Academic and Public Libraries [PDF]
, 2020 Academic and public library collections are developed based on the needs of the communities that surround them. Technology has increased the way users access information, and the way libraries offer information to their users.
DiGiovanni, Anthony M
core +1 more source