Results 91 to 100 of about 1,855,697 (337)
Evolutionary interplay between viruses and R‐loops
Viruses interact with specialized nucleic acid structures called R‐loops to influence host transcription, epigenetic states, latency, and immune evasion. This Perspective examines the roles of R‐loops in viral replication, integration, and silencing, and how viruses co‐opt or avoid these structures.
Zsolt Karányi+4 more
wiley +1 more source
What do MOOC providers think about accessibility? [PDF]
Massive Online Open Courses (MOOCs) have become an accepted way to make learning opportunities available at large scale and low cost to the learner. However, only if these are made accessible will they be able to offer the flexibility of learning and ...
Coughlan, Tim+3 more
core
If the year 2000 was important for dentistry, the current year may turn out to be even more of a turning point. Once the general election is out of the way there should be a new mood of confidence within the Labour Party. The possibility of a Tory victory seems remote, unless foot and mouth disease gets the better of Tony Blair, and the pre-election ...
openaire +2 more sources
Disruption of SETD3‐mediated histidine‐73 methylation by the BWCFF‐associated β‐actin G74S mutation
The β‐actin G74S mutation causes altered interaction of actin with SETD3, reducing histidine‐73 methylation efficiency and forming two distinct actin variants. The variable ratio of these variants across cell types and developmental stages contributes to tissue‐specific phenotypical changes. This imbalance may impair actin dynamics and mechanosensitive
Anja Marquardt+8 more
wiley +1 more source
This study uses accessibility as a performance measure to evaluate a matrix of future land use and network scenarios for planning purposes. Previous research has established the coevolution of transportation and land use, demonstrated the dependence of ...
David Levinson+2 more
core
When Is Open Access Not Open Access?
As open access grows in prominence, so too has confusion about what open access means; such confusion arises from a genuine misunderstanding of open access by funders, authors, editors, and publishers alike.
openaire +4 more sources
Purification tags markedly affect self‐aggregation of CPEB3
Although recombinant proteins are used to study protein aggregation in vitro, uncleaved tags can interfere with accurate interpretation. Our findings demonstrate that His₆‐GFP and His₁₂ tags significantly affect liquid droplet and amyloid fibril formation in the intrinsically disordered region (IDR) of mouse cytoplasmic polyadenylation element‐binding ...
Harunobu Saito+6 more
wiley +1 more source
Crowdsourcing e-book accessibility information and the impact on staff development
For students with print impairments, e-books offer great potential to remove barriers to information. However, for various reasons, not all e-books are fully accessible. Significant variability exists between different platforms and titles.
Victoria Dobson, Alistair McNaught
doaj +1 more source
Accessibility of websites of the European national tourism boards [PDF]
Purpose: The aim is to find out the current state of accessibility of the websites of European national tourism boards. Furthermore, the identification of the most common errors in terms of accessibility as well as recommendations leading to their ...
Abrhám, Josef+3 more
core
Circulating histones as clinical biomarkers in critically ill conditions
Circulating histones are emerging as promising biomarkers in critical illness due to their diagnostic, prognostic, and therapeutic potential. Detection methods such as ELISA and mass spectrometry provide reliable approaches for quantifying histone levels in plasma samples.
José Luis García‐Gimenez+17 more
wiley +1 more source