Results 111 to 120 of about 682,030 (316)

An AI-driven framework integrating predictive modeling and intervention strategies to enhance psychological health education among college students

Discover Applied Sciences
The increasing incidence of psychological health challenges among college students highlights the limitations of traditional education and intervention methods.
Xinyuan Zhang, Wanbing Shi
doaj   +1 more source

Write accessibly [PDF]

Nature Biomedical Engineering, 2021
openaire   +2 more sources

Open access [PDF]

British Dental Journal, 2021
openaire   +2 more sources

The role of histone modifications in transcription regulation upon DNA damage

FEBS Letters, EarlyView.
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley   +1 more source

Efficient Machine Learning Models for Solar Radiation Prediction Using Ensemble Techniques: A Case Study in Low-Rainfall Arid Climates

IEEE Access
Solar energy is a green energy source that can be used to generate electricity, making it one of the oldest existing renewable energy sources. However, solar energy values are not always available in many areas far from urban cities, due to the high cost
Jimmy Aurelio Rosales Huamani, Uwe Rojas Villanueva, Christian Leonardo Rosales Ventocilla, Jose Luis Castillo Sequera, Jose Manuel Gomez Pulido   +4 more
doaj   +1 more source

Substrate specificity of Burkholderia pseudomallei multidrug transporters is influenced by the hydrophilic patch in the substrate‐binding pocket

FEBS Letters, EarlyView.
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley   +1 more source

Tucaresol: A Unique Oral Candidate Drug Ideally Accessible for Treatment of COVID-19 Disease

, 2022
Christopher Penney, Boulos Zacharie, Jean‐Simon Duceppe   +2 more
openalex   +2 more sources

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source

Concerning Accessibility [PDF]

Proceedings of the National Academy of Sciences, 1939
openaire   +2 more sources

Time after time – circadian clocks through the lens of oscillator theory

FEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo, Carolin Ector, Hanspeter Herzel   +2 more
wiley   +1 more source