Results 171 to 180 of about 5,932,199 (300)

Assessing physical-exercise suitability in an urban canal corridor: evidence from the Cangzhou reach of China's Grand Canal. [PDF]

Front Public Health
Zhang X, Zhong W, Yu Y, Cao L.
europepmc   +1 more source

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

FEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos, Antonia Petropoulou, Alexandra Anastogianni, Angelina Bania, Vassilis Stamatakis, Argyris Alexiou, Chi‐Ping Day, Glenn Merlino, Katerina Grafanaki, Constantinos Stathopoulos   +9 more
wiley   +1 more source

Gradient-based optimization for mRNA sequence design. [PDF]

Bioinformatics
Li H, Terai G, Otagaki T, Asai K.
europepmc   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source

Media exposure, perceived stereotype accessibility, and national image formation: experimental and short-term panel evidence from Chinese perceptions of Germany. [PDF]

Front Psychol
Chen Z, Sun W.
europepmc   +1 more source

Smaller is better: nanobodies meet NMR

FEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source

Algorithmic fairness in AI-based fitness advice: evaluating socioeconomic bias in county-contextualized physical activity prescriptions. [PDF]

Front Public Health
Bao H, Yu T, Wang J, Yin H, Gao Y, Mao Y.   +5 more
europepmc   +1 more source

Invisible but not inaccessible—Revealing transient oligomers formed by intrinsically disordered proteins with solution NMR and complementary methods

FEBS Letters, EarlyView.
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley   +1 more source

Application of gamification elements in accessibility testing

reservedThe concept accessibility means that a device, a service, a resource or an environment must be easily perceivable and usable by any user. More specifically, Web Accessibility means that the Web is designed so that everyone even people with ...
LLESHI, GERTA
core  

Deep Learning for Deciphering the Plant Cis-Regulatory Code. [PDF]

Plants (Basel)
Zhao Z, Huang S, Zhang S, Li C, Chao H, Wang Z, Zheng X, Feng C, Chen M.   +8 more
europepmc   +1 more source