Results 61 to 70 of about 126,941 (295)

Postcopulatory sexual selection [PDF]

, 2002
The female reproductive tract is where competition between the sperm of different males takes place, aided and abetted by the female herself. Intense postcopulatory sexual selection fosters inter-sexual conflict and drives rapid evolutionary change to ...
A Civetta, A Singson, A Singson, AB Carvalho, AJ Bateman, AK Chippindale, AK Chippindale, AP Møller, AP Møller, B Hellriegel, B Holland, B Kempenaers, BC Sheldon, BC Sheldon, BT Preston, C Darwin, CW LaMunyon, D Carré, D Childress, D Haig, D Hosken, D Pfaff, D Vacquier, D Yamamoto, DA Roff, DB Lank, DC Presgraves, DC Shakes, DJ Begun, DJ Hosken, DM Rand, DW Coltman, E Ottaviano, E Ruiz-Pesini, EC Metz, ED Ketterson, EH Nicholls, EJA Cunningham, FD Karim, FM Hunter, FM Hunter, G Arnqvist, G Arnqvist, GA Parker, GA Parker, GA Parker, GA Parker, GA Parker, GA Parker, H Montell, HDM Moore, IM Matthews, J Nance, JB Wolf, JDD Bishop, JHJ Van der Werf, JK Waage, JM Cheverud, JM Martin-Villa, JS Takahashi, JV Briskie, JV Briskie, K Uchida, KA Hughes, L Andersson, L Delph, L Keller, LD Hurst, LW Simmons, LW Simmons, M Andersson, M Edvardsson, M Lynch, M Ridley, MK Dahle, N Wilson, P David, P Jivoff, P Stockely, P Stockley, P Ward, P Ward, PA Cook, PS Chen, R Lande, R Thornhill, RD Catalano, RL Smith, RL Smith, RL Trivers, RR Baker, RR Snook, RR Snook, RR Warner, S Gavrilets, S Palumbi, S Pitnick, S Pitnick, S Pitnick, S Stearns, SA Frank, SM Shuster, SM Shuster, SW L' Hernault, T Chapman, T Chapman, T Chapman, T Pizzari, T Pizzari, T Prout, T Prout, T Tregenza, T Tregenza, TFC Mackay, TH Clutton-Brock, TM Panhuis, TR Birkhead, TR Birkhead, TR Birkhead, TR Birkhead, TR Birkhead, TR Birkhead, TR Halliday, UW Huck, W Swanson, WG Eberhard, WJ Swanson, WJ Swanson, WJ Swanson, WJ Swanson, WR Rice, WR Rice, WR Rice   +132 more
core   +1 more source

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

Molecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto, Louise Raunkilde, Jan Lindebjerg, Mads Malik Aagaard, Christina Therkildsen, Jakob Kleif, Lars Henrik Jensen, Torben Frøstrup Hansen, Rikke Fredslund Andersen   +8 more
wiley   +1 more source

Destabilization of the Tumor-Inducing Plasmid from an Octopine-Type Agrobacterium tumefaciens Lineage Drives a Large Deletion in the Co-resident At Megaplasmid

G3: Genes, Genomes, Genetics, 2019
Bacteria with multi-replicon genome organizations, including members of the family Rhizobiaceae, often carry a variety of niche-associated functions on large plasmids.
Ian S. Barton, Thomas G. Platt, Douglas B. Rusch, Clay Fuqua   +3 more
doaj   +1 more source

Local adaptation drives the diversification of effectors in the fungal wheat pathogen Parastagonospora nodorum in the United States

, 2019
Filamentous fungi rapidly evolve in response to environmental selection pressures in part due to their genomic plasticity. Parastagonospora nodorum, a fungal pathogen of wheat and causal agent of septoria nodorum blotch, responds to selection pressure ...
Carpenter, J., Cowger, C., Faris, J., Friesen, T., Liu, Z., Richards, J., Stukenbrock, E.   +6 more
core   +1 more source

Lineage A betacoronavirus NS2 proteins and the homologous torovirus Berne pp1a carboxy-terminal domain are phosphodiesterases that antagonize activation of RNase L [PDF]

, 2017
Viruses in the family Coronaviridae, within the order Nidovirales, are etiologic agents of a range of human and animal diseases, including both mild and severe respiratory diseases in humans.
Chen, Annie I, Elliott, Ruth, Goldstein, Stephen A, Jha, Babal K, Li, Yize, Quiroz-Figueroa, Katherine, Silverman, Robert H, Thornbrough, Joshua M, Weiss, Susan R, Zhang, Rong   +9 more
core   +2 more sources

Monitoring of circulating tumor DNA allows early detection of disease relapse in patients with operable breast cancer

Molecular Oncology, EarlyView.
Monitoring circulating tumor DNA (ctDNA) in patients with operable breast cancer can reveal disease relapse earlier than radiology in a subset of patients. The failure to detect ctDNA in some patients with recurrent disease suggests that ctDNA could serve as a supplement to other monitoring approaches.
Kristin Løge Aanestad, Marie Austdal, Oddmund Nordgård, Gunnar Mellgren, Satu Oltedal, Marie L. Austbø, Ylva H. Vignes, Thomas Helland, Kristin Jonsdottir, Tone H. Lende, Emilius A. M. Janssen, Bjørnar Gilje, Kjersti Tjensvoll, PBCB study group, Gunnar Mellgren, Tone Hoel Lende, Anette Heie, Kristin Viste, Anita Røyneberg Alvheim, Emiel AM Janssen, Kristin Jonsdottir, Ann Cathrine Kroksveen, Thomas Helland, Einar Gudlaugsson, Oddmund Nordgård, Satu Oltedal, Kristin Løge Aanestad, Jan Terje Kvaløy, Kirsten Lode, Kari Britt Hagen, Marie Austdal, Ylva H. Vignes, Siri Tungland Sola, Nina Egeland Amundsen, Finn Magnus Eliassen, Emeritus Ernst A Lien   +35 more
wiley   +1 more source

Phage inducible islands in the gram-positive cocci [PDF]

, 2016
The SaPIs are a cohesive subfamily of extremely common phage-inducible chromosomal islands (PICIs) that reside quiescently at specific att sites in the staphylococcal chromosome and are induced by helper phages to excise and replicate.
A Bolotin, A Chopin, A Ruzin, B Frígols, BA Duerkop, C Ubeda, C Ubeda, C Ubeda, C Ubeda, C Ubeda, CH O'Callaghan, CM Hamilton, D Straume, D Viana, Davida Smyth, E Charpentier, E Maiques, G Ram, G Ram, Geeta Ram, IT Paulsen, J Chen, J Chen, J Chen, J Scott, J Scott, J-P Claverys, JA Lindsay, John Chen, José R Penadés, JR Penadés, M Kanehisa, MA Tormo, MD Ferrer, Miguel Martí, MÁ Tormo-Más, MÁ Tormo-Más, N Carpena, N Quiles-Puchalt, N Quiles-Puchalt, Nuria Quiles-Puchalt, RC Matos, Richard P Novick, Roser Martínez-Rubio, RP Novick, RP Novick, Suzanne Humphrey, SV Nguyen   +47 more
core   +1 more source

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

Molecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone, James Dunford, Eleanor Calcutt, Vicki Gamble, Filiz Senbabaoglu Aksu, Lorena Ligammari, Georgina Wherry, Giorgia Gaeta, John C. Christianson, Adrienne M. Flanagan, Udo Oppermann, Adam P. Cribbs   +11 more
wiley   +1 more source

Exploring the Genomic Traits of Non-toxigenic Vibrio parahaemolyticus Strains Isolated in Southern Chile

Frontiers in Microbiology, 2018
Vibrio parahaemolyticus is the leading cause of seafood-borne gastroenteritis worldwide. As reported in other countries, after the rise and fall of the pandemic strain in Chile, other post-pandemic strains have been associated with clinical cases ...
Daniel Castillo, Diliana Pérez-Reytor, Nicolás Plaza, Sebastián Ramírez-Araya, Sebastián Ramírez-Araya, Carlos J. Blondel, Gino Corsini, Roberto Bastías, David E. Loyola, Víctor Jaña, Leonardo Pavez, Leonardo Pavez, Katherine García   +12 more
doaj   +1 more source

Comparative genomics of Shiga toxin encoding bacteriophages [PDF]

, 2012
Background Stx bacteriophages are responsible for driving the dissemination of Stx toxin genes (stx) across their bacterial host range. Lysogens carrying Stx phages can cause severe, lifethreatening disease and Stx toxin is an integral virulence factor.
Allison, Heather, Darby, Alistair, Fogg, Paul, McCarthy, Alan, Rooks, David, Smith, Darren, Thomson, Nicholas   +6 more
core   +2 more sources