Results 61 to 70 of about 196,672 (357)

ALDOA Promotes Glycolysis and NLRP3/GSDMD Pyroptosis to Accelerate ALS Progression

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is characterized by progressive motor neuron degeneration. Glycolytic dysregulation is implicated in disease progression, yet the underlying mechanisms remain unclear. This study investigates how Aldolase A (ALDOA) drives ALS progression through glycolysis‐mediated motor neuron pyroptosis.
Kaixin Yan, Yan Jiang, Yuxuan Yong, Tianshuo Zhang, Niannian Zhang, Qianqian Zeng, Xue Gong, Li Meng, Fangfang Bi, Yongmin Liu   +9 more
wiley   +1 more source

Uncovering Spatio-Temporal and Treatment-Derived Differences in the Molecular Physiology of a Model Coral-Dinoflagellate Mutualism with Multivariate Statistical Approaches

Journal of Marine Science and Engineering, 2016
In light of current global climate change forecasts, there is an urgent need to better understand how reef-building corals respond to changes in temperature.
Anderson B. Mayfield
doaj   +1 more source

Existing antioxidant levels are more important in acclimation to supplemental UV-B irradiation than inducible ones: Studies with high light pretreated tobacco leaves [PDF]

, 2012
Greenhouse grown tobacco plants were exposed to supplemental ultraviolet irradiation (280-400 nm, UV-B centered) for 6 days and changes in their photosynthesis (gas exchange and electron transport) and general and specific antioxidant activities were ...
Hideg, Éva, Majer, Petra
core   +1 more source

The Role of Calcitonin Gene‐Related Peptide in High‐Altitude Headache: A Prospective Field Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective High‐altitude headache (HAH) is a common neurological condition associated with rapid ascent to high altitude. The pathophysiological mechanisms underlying HAH remain incompletely understood. Calcitonin gene‐related peptide (CGRP), a neuropeptide implicated in migraine pathophysiology, may play a key role in the pathophysiology of ...
Roman Schniepp, Ludwig Karrasch, Helena Breitenstein, Andreas Straube, Katharina Kamm   +4 more
wiley   +1 more source

Genetic Variations and Differential DNA Methylation to Face Contrasted Climates in Small Ruminants: An Analysis on Traditionally-Managed Sheep and Goats

Frontiers in Genetics, 2021
The way in which living organisms mobilize a combination of long-term adaptive mechanisms and short-term phenotypic plasticity to face environmental variations is still largely unknown.
Laure Denoyelle, Laure Denoyelle, Pierre de Villemereuil, Frédéric Boyer, Meidhi Khelifi, Clément Gaffet, Florian Alberto, Badr Benjelloun, Badr Benjelloun, François Pompanon   +9 more
doaj   +1 more source

PEDOT‐Based Eutectogel Electrode Arrays for Enhanced High‐Resolution Electrogastrography: Fabrication, Stability, and Wearable Performance

Advanced Functional Materials, EarlyView.
Here, we present a high‐density PEDOT eutectogel electrode array for enhanced body surface gastric mapping. Silver electrodes are blade‐coated onto flexible substrates, followed by electrogelation of PEDOT:PSS and the deposition of a PEDOT:LS eutectogel.
Christopher Slaughter, Luke Gatecliff, Xudong Tao, Ruben Ruiz‐Mateos Serrano, Amy T. Jin, Matias L. Picchio, Daniele Mantione, Antonio Dominguez‐Alfaro, George G. Malliaras   +8 more
wiley   +1 more source

The coordination of gene expression within photosynthesis pathway for acclimation of C4 energy crop Miscanthus lutarioriparius

Frontiers in Plant Science, 2016
As a promising candidate for the second-generation C4 energy crop, Miscanthus lutarioriparius has well acclimated to the water-limited and high-light Loess Plateau in China by improving photosynthesis rate and water use efficiency (WUE) compared to its ...
Shilai eXing, Shilai eXing, Lifang eKang, Qin eXu, Yangyang eFan, Yangyang eFan, Wei eLiu, Caiyun eZhu, Caiyun eZhu, Zhihong eSong, Zhihong eSong, Qian eWang, Qian eWang, Juan eYan, Jianqiang eLi, Tao eSang, Tao eSang   +16 more
doaj   +1 more source

The effect of fasting on the glycogen metabolism in heat-acclimated rats [PDF]

Archives of Biological Sciences, 2008
We investigated the influence of successive fasting for 24,48,72, and 96 h on some key enzymes and substrates of liver, kidney, and muscle in control and heat-acclimated (30days at 35 ± 1°C)rats.
Miova Biljana, Dinevska-Kjovkarevska Suzana, Mitev S., Dervišević Mirsada   +3 more
doaj   +1 more source

Intraspecfic variation in cold-temperature metabolic phenotypes of Arabidopsis lyrata ssp petraea [PDF]

, 2009
Atmospheric temperature is a key factor in determining the distribution of a plant species. Alongside this, plant populations growing at the margin of their range may exhibit traits that indicate genetic differentiation and adaptation to their local ...
A Suzuki, AB Bleeckerl, B Jonsell, B Usadel, B Vinocur, BH Miesak, C Alonso-Blanco, CD Thomas, CL Guy, D Cook, F Kaplan, F Kaplan, F. Ian Woodward, GR Gray, GR Walther, GR Walther, HM Lam, HM Lam, HM Lam, IC Oliveira, J Kilian, J Klotke, L Skøt, M Stitt, MA Hannah, Matthew P. Davey, MF Thomashow, MJ Clauss, MJ Clauss, MP Davey, N Smirnoff, NR Sackville Hamilton, OK Atkin, P Vergeer, RC Meyer, RJ Li, S Sagisaka, TK Peterman, W. Paul Quick, Y Zhen, Å Strand   +40 more
core   +1 more source

Highly Conductive and Stretchable Photothermal CuSe Fiber for Wearable Electronics and Implantable Drug Release Systems

Advanced Functional Materials, EarlyView.
The conductive and stretchable photothermal CuSe fiber is fabricated for versatile biomedical applications. This CuSe fiber functions as a reliable wearable strain sensor and heater due to its high conductivity, stretchability and photothermal efficiency.
Kukro Yoon, Yukye Lee, Sang Ki Rhee, Hyeonjoo Park, Kyowon Kang, Mingyu Sang, Byeonggwan Kim, Jung Seung Lee, Jaehong Lee, Taeyoon Lee   +9 more
wiley   +1 more source