Results 101 to 110 of about 77,920 (347)

The Danger of Indiscriminate Acclimatization in the Case of Mammals and Birds [PDF]

, 1899
T. S. Palmer
openalex   +1 more source

Performance of Acclimatized Mice at Altitude

Experimental Biology and Medicine, 1954
SummaryMice acclimatized to one altitude (350 mm Hg) showed an increase in performance when exposed to a higher altitude (247 mm Hg) as compared with ground level controls. When acclimatized mice are bled they showed a decrease in their performance level.
F. G. Hall, June Barker
openaire   +3 more sources

Alnustone Ameliorates Metabolic Dysfunction‐Associated Steatotic Liver Disease by Facilitating Mitochondrial Fatty Acid β‐Oxidation via Targeting Calmodulin

Advanced Science, EarlyView.
This study identifies alnustone, a natural compound from Alpinia katsumadai, as a potent therapeutic agent for MASLD and MASH. Alnustone enhances mitochondrial fatty acid β‐oxidation by directly targeting calmodulin, improving liver steatosis, fibrosis, and insulin resistance in vivo.
Shourui Hu, Xiaofan Liang, Yiming Qin, Yuxuan Li, Yue Liu, Congcong Liu, Zongxuan Lin, Chunxuan Geng, Yanqi Xu, Daimin Wei, Yingying Qin, Han Zhao, Yuqing Zhang, Zi‐Jiang Chen   +13 more
wiley   +1 more source

Metabolite Modulation in Human Plasma in the Early Phase of Acclimatization to Hypobaric Hypoxia

Scientific Reports, 2016
The exposure of healthy subjects to high altitude represents a model to explore the pathophysiology of diseases related to tissue hypoxia. We explored a plasma metabolomics approach to detect alterations induced by the exposure of subjects to high ...
Wen-Ting Liao, Bao Liu, Jian Chen, J. Cui, Yi-Xing Gao, Fu-yu Liu, Gang Xu, Bing-Da Sun, Erlong Zhang, Zhibin Yuan, Gang Zhang, Yu-qi Gao   +11 more
semanticscholar   +1 more source

The LDH‐H3K18La‐Nur77 Axis Potentiates Immune Escape in Small Cell Lung Cancer

Advanced Science, EarlyView.
Lactate from SCLC tumors induces H3K18 lactylation in naïve CD8+ T cells, upregulating Nurr77 and enhancing tonic TCR signaling. This leads to T cell hyporesponsiveness to stimulation, impairing antitumor immunity and reducing immunotherapy efficacy.
Xiaoling Shang, Bo Cheng, Chenyue Zhang, Chenglong Zhao, Ruiqing Wang, Xun Zhang, Dizhi Jiang, Xinyu Zhang, Xinyue Ma, Hongyuan Mao, Zerun Li, Chenhan Huang, Tianzi Wang, Kaiyue Guo, Liwen Wang, Ning Tang, Haiyong Wang   +16 more
wiley   +1 more source

A relative quantitative Methylation-Sensitive Amplified Polymorphism (MSAP) method for the analysis of abiotic stress

BMC Plant Biology, 2017
Background We present a new methylation-sensitive amplified polymorphism (MSAP) approach for the evaluation of relative quantitative characteristics such as demethylation, de novo methylation, and preservation of methylation status of CCGG sequences ...
Piotr T. Bednarek, Renata Orłowska, Agnieszka Niedziela   +2 more
doaj   +1 more source

Acclimatization as a factor affecting the upper thermal death points of organisms [PDF]

, 1919
M Jacobs
openalex   +1 more source

Soft Bioelectronic Interfaces for Continuous Peripheral Neural Signal Recording and Robust Cross‐Subject Decoding

Advanced Science, EarlyView.
A soft poly (3,4‐ethylenedioxythiophene):poly (styrenesulfonate)‐based electrode enables continuous, high‐quality recording of peripheral nerve activity. A neural network model integrating handcrafted and convolutional neural network‐based features decodes whisker movements with strong generalization, offering insights into peripheral nerve function ...
Liangpeng Chen, Yang Liu, Yewei Huang, Ziyang Li, Chao Zhang, Jun Tang, Xueyuan Ling, Bowen Cao, Baowang Li, Yuan Zhang, Wenjianlong Zhou, Qin Xu, Shunchang Ma, Xiudong Guan, Dan Xiao, Jingyao Geng, Yutong Zhao, Guolin Li, Yi‐xuan Wang, Wang Jia, Yuanwen Jiang, Milin Zhang, Deling Li   +22 more
wiley   +1 more source

Mesophotic coral depth acclimatization is a function of host-specific symbiont physiology

Frontiers in Marine Science, 2015
Mesophotic coral ecosystems receive increasing attention owing to their potential as deep coral refuges in times of global environmental change. Here, the mechanisms of coral holobiont photoacclimatization over a 60 m depth gradient in the central Red ...
M. Ziegler, Cornelia M. Roder, C. Büchel, C. Voolstra   +3 more
semanticscholar   +1 more source

Listerin Alleviates Alzheimer's Disease through IRE1‐mediated Decay of TLR4 mRNA

Advanced Science, EarlyView.
Alzheimer's disease (AD) progression is influenced by microglia‐mediated neuroinflammation. Here, it is demonstrated that Listerin suppresses neuroinflammatory signaling and cognitive impairment in AD models by triggering IRE1α‐mediated TLR4 mRNA decay. Adenoviral Listerin delivery reduces amyloid‐β pathology, positioning it as a new therapeutic target.
Fei Qin, Runyu Cao, Xuemei Bai, Jiahua Yuan, Wanwei Sun, Yi Zheng, Xiaopeng Qi, Wei Zhao, Bingyu Liu, Chengjiang Gao   +9 more
wiley   +1 more source