Results 51 to 60 of about 26,550 (306)

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Research progress in visual fatigue related to stereoscopic video display terminals

open access: yesShanghai Jiaotong Daxue xuebao. Yixue ban, 2023
In recent years, with the development of science and technology, stereoscopic video display terminals have become more and more widely used in many fields.
LIU Lu, KE Bilian
doaj   +1 more source

Heroin withdrawal as a possible cause of acute concomitant esotropia in adults [PDF]

open access: yes, 2001
Aim: To report the possible effects of heroin withdrawal on binocular vision. Methods: To present a case series of patients in whom esotropia developed on cessation of heroin use.
Firth, A.Y.
core  

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Statistical Model of Ocular Wavefronts With Accommodation

open access: yesInvestigative Ophthalmology & Visual Science
The purpose of this study was to determine the minimum number of orthonormal basis functions, applying Principal Component Analysis (PCA), to represent the most wavefront aberrations at different accommodation stages. The study also aims to generate synthetic wavefront data using these functions.Monocular wavefront data from 191 subjects (26.15 ± 5.56 ...
Mechó-García, María   +9 more
openaire   +6 more sources

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

open access: yesFEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas   +3 more
wiley   +1 more source

High-Order Aberrations: A Key Factor in Accommodative Dysfunctions

open access: yesApplied Sciences
This study investigated the relationship between high-order aberrations (HOAs) and accommodative dysfunctions by analyzing their changes with accommodation.
Jessica Gomes, Sandra Franco
doaj   +1 more source

Down syndrome: a review of ocular manifestations

open access: yesTherapeutic Advances in Ophthalmology, 2022
Down syndrome is the most common genetically mediated intellectual disability. Although many physiologic and pathologic features of Down syndrome are discussed at length in the literature, the ocular manifestations of Down syndrome have seldom been ...
Abid Haseeb   +7 more
doaj   +1 more source

Eye movements in mild traumatic brain injury: Ocular biomarkers

open access: yesJournal of Eye Movement Research, 2022
Mild traumatic brain injury (mTBI, or concussion), results from direct and indirect trauma to the head (i.e. a closed injury of transmitted forces), with or without loss of consciousness.
Matthew A. McDonald   +2 more
doaj   +1 more source

Short-Term Adaptive Modification of Dynamic Ocular Accommodation [PDF]

open access: yesInvestigative Opthalmology & Visual Science, 2009
Indirect observations suggest that the neural control of accommodation may undergo adaptive recalibration in response to age-related biomechanical changes in the accommodative system. However, there has been no direct demonstration of such an adaptive capability.
Shrikant R, Bharadwaj   +2 more
openaire   +2 more sources

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