Results 51 to 60 of about 12,483 (262)

Electron transfer between complexes III and IV in S. cerevisiae mitochondrial membranes

FEBS Letters, EarlyView.
Mitochondrial oxidative phosphorylation in S. cerevisiae mitoplasts is limited by complex IV catalytic capacity, rather than two‐dimensional cytochrome c diffusion. At physiological cytochrome c : supercomplex ratios at salinity equivalent to that of 20 mm monovalent salt, activity is maximized, indicating that this low ionic strength accurately mimics
Ana Paula Lobez, Mikael Oliveberg, Peter Brzezinski   +2 more
wiley   +1 more source

The difference in accommodative amplitude and facility between the dominant and non-dominant eyes

Journal of the Pakistan Medical Association
The cross-sectional study was planned to compare the amplitude of accommodation and accommodative facility between the dominant and non-dominant eyes in young university students.
Basal Hamad Altoaimi
doaj   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

Prevalence of Near-Vision-Related Symptoms in a University Population

Vision
The university population has high visual demands. It is therefore important to assess the prevalence of symptoms in these subjects, which may affect their academic performance.
Jessica Gomes, Sandra Franco
doaj   +1 more source

Latanoprost could exacerbate the progression of presbyopia.

PLoS ONE, 2019
PURPOSE:Prostaglandin analogues (PG) reduce intra-ocular pressure by enhancing uveoscleral flow at the ciliary body, which controls accommodation via the ciliary muscle.
Masahiko Ayaki, Yukari Tsuneyoshi, Kenya Yuki, Kazuo Tsubota, Kazuno Negishi   +4 more
doaj   +1 more source

Neural Control of Vergence and Ocular Accommodation

Annual Review of Vision Science
We review the current state of our knowledge of the neural control of vergence and ocular accommodation in primates including humans. We first describe the critical need for these behaviors for viewing in a three-dimensional world. We then consider the sensory stimuli that drive vergence eye movements and lens accommodation and describe models of the ...
Julie, Quinet, Kevin, Schultz, Paul J, May, Paul D, Gamlin   +3 more
openaire   +2 more sources

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

FEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi, João C. Encarnação, Valeria Napolitano, Grzegorz Dubin, Grzegorz Popowicz, Karl Andersson, U. Helena Danielson   +6 more
wiley   +1 more source

Evaluation of Ocular Complications in Intraoral Local Anesthesia

Journal of Pharmacy and Bioallied Sciences
Background: The most significant medications in dentistry are local anesthetics, and intraoral local anesthesia is arguably the most used dental procedure. However, complications have also been reported.
Rameet Sandhu, Vikas Sikarwar, Sushil Ojha, Dushyant Upadhyay, Anshdeep Singh, Shweta Sharma   +5 more
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source