Results 61 to 70 of about 26,550 (306)

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Effects of Visual Display Unit on Ocular Accommodation in Young Adults

British and Irish Orthoptic Journal
Purpose: To evaluate the impact of gaming on ocular accommodative parameters. Methods: A comparative and experimental study was conducted among non-orthoptic university students for a duration of six months from September 2023 to March 2024. After a half-
Vishal Biswas, Roshni Majumder
doaj   +1 more source

Axial movement of the dual-optic accommodating intraocular lens for the correction of the presbyopia: Optical performance and clinical outcomes

Journal of Optometry, 2015
Presbyopia occurs in the aging eye due to changes in the ciliary muscle, zonular fibers, crystalline lens, and an increased lens sclerosis. As a consequence, the capacity of accommodation decreases, which hampers to focus near objects.
Javier Tomás-Juan, Ane Murueta-Goyena Larrañaga   +1 more
doaj   +1 more source

Accommodative convergence–accommodation ratio and fusional capacity in patients with constant and intermittent exotropia

Journal of Ophthalmology, 2021
Background: It has been reported that exotropia was seen in 16.9-23% of patients with strabismus. Exophoria and exotropia may be caused by congenital or acquired anomalies in orbital structure, ocular structure, or extraocular muscle attachment and/or ...
I. M. Boichuk, Alui Tarak
doaj   +1 more source

Media use during adolescence: the recommendations of the Italian Pediatric Society. [PDF]

, 2019
BACKGROUND: The use of media device, such as smartphone and tablet, is currently increasing, especially among the youngest. Adolescents spend more and more time with their smartphones consulting social media, mainly Facebook, Instagram and Twitter ...
Agostiniani R, Banderali G, Bozzola E, Bozzola M, Caruso C, Chiara A, Corsello G, Del Vecchio A, Memo L, Peroni D, Ruggiero M, Spina G, Staiano AM, Turra R, Vecchio D, Villani A   +15 more
core   +2 more sources

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

Molecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix, Daniel Samaga, Katharina Gehr, Benedek Dankó, Mohamed Schumann, Guido Drexler, Ahmed Alnatsha, Georg Beyer, Ujjwal Mahajan, Martin Selmansberger, Julia Mayerle, Claus Belka, Horst Zitzelsberger, Kirsten Lauber   +13 more
wiley   +1 more source

Pattern-Related Visual Stress, Chromaticity, and Accommodation [PDF]

, 2010
PURPOSE. To investigate the impact of colored overlays on the accommodative response of individuals, with and without pattern- related visual stress (PRVS), a condition in which individuals manifest symptoms of perceptual distortion and discomfort when ...
Allen, Peter M, Hussain, Atif, Usherwood, Claire, Wilkins, Arnold J   +3 more
core   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source

The difference in accommodative amplitude and facility between the dominant and non-dominant eyes

Journal of the Pakistan Medical Association
The cross-sectional study was planned to compare the amplitude of accommodation and accommodative facility between the dominant and non-dominant eyes in young university students.
Basal Hamad Altoaimi
doaj   +1 more source

Orthoptic status before and immediately after heroin detoxification [PDF]

, 2004
Aim: To determine whether changes in orthoptic status take place during withdrawal from heroin and/or methadone. Method: A prospective study of patients, using a repeated measures design, attending a 5 day naltrexone compressed opiate detoxification ...
Beaini, A.Y., Carr, M.P., Firth, A.Y., Pulling, S.   +3 more
core   +2 more sources