Results 61 to 70 of about 314,600 (296)

Effects of Visual Display Unit on Ocular Accommodation in Young Adults

open access: yesBritish and Irish Orthoptic Journal
Purpose: To evaluate the impact of gaming on ocular accommodative parameters. Methods: A comparative and experimental study was conducted among non-orthoptic university students for a duration of six months from September 2023 to March 2024. After a half-
Vishal Biswas, Roshni Majumder
doaj   +1 more source

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

open access: yesFEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav   +2 more
wiley   +1 more source

The role of inflammation and fibroblasts in conjunctival scarring in ocular mucous membrane pemphigoid [PDF]

open access: yes, 2009
Ocular mucous membrane pemphigoid (ocular MMP) is a visually devastating disease where up to 30% of patients become blind due to the consequences of conjunctival inflammation and aggressive fibrosis.
Saw, V.P.J.
core  

The difference in accommodative amplitude and facility between the dominant and non-dominant eyes

open access: yesJournal of the Pakistan Medical Association
The cross-sectional study was planned to compare the amplitude of accommodation and accommodative facility between the dominant and non-dominant eyes in young university students.
Basal Hamad Altoaimi
doaj   +1 more source

Artificial molecular machines and motors—Design and control of nanoscale motion

open access: yesFEBS Letters, EarlyView.
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley   +1 more source

Prevalence of Near-Vision-Related Symptoms in a University Population

open access: yesVision
The university population has high visual demands. It is therefore important to assess the prevalence of symptoms in these subjects, which may affect their academic performance.
Jessica Gomes, Sandra Franco
doaj   +1 more source

Neural Control of Vergence and Ocular Accommodation

open access: yesAnnual Review of Vision Science
We review the current state of our knowledge of the neural control of vergence and ocular accommodation in primates including humans. We first describe the critical need for these behaviors for viewing in a three-dimensional world. We then consider the sensory stimuli that drive vergence eye movements and lens accommodation and describe models of the ...
Julie, Quinet   +3 more
openaire   +2 more sources

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

open access: yesMolecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder   +10 more
wiley   +1 more source

Down syndrome: a review of ocular manifestations

open access: yesTherapeutic Advances in Ophthalmology, 2022
Down syndrome is the most common genetically mediated intellectual disability. Although many physiologic and pathologic features of Down syndrome are discussed at length in the literature, the ocular manifestations of Down syndrome have seldom been ...
Abid Haseeb   +7 more
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

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