Results 81 to 90 of about 12,436 (263)
RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells
FEBS Open Bio, EarlyView.RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour +2 more
wiley +1 more source
Influence of Blood Glycemia Levels in Refraction, Binocular Vision and Accommodation: A Case Report
ReportsThis case report provides us with insight on how blood glycemia affects refraction, vergence and accommodation in a single diabetic patient. A 21-year-old type I diabetic woman was the subject studied in this report.
Marc Argilés +4 more
doaj +1 more source
Directed evolution of enzymes at the crossroads of tradition and innovation
FEBS Open Bio, EarlyView.An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova +2 more
wiley +1 more source
Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1
FEBS Open Bio, EarlyView.The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay +2 more
wiley +1 more source
Dry eye disease ranking among common reasons for seeking eye care in a large US claims database
Clinical Ophthalmology, 2019 John L Bradley,1,2 Ipek Özer Stillman,3 Irina Pivneva,4 Annie Guerin,4 Amber M Evans,5 Reza Dana6 1Naval Medical Research Unit Dayton, Vision Science Lab, Wright Patterson AFB, OH, USA; 2University of Pikeville, Kentucky College of Optometry ...
Bradley JL +5 more
doaj
FEBS Open Bio, EarlyView.The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley +1 more source
Ultrasound biomicroscopy insights: Ciliary body changes during accommodation in young adults
The Pan-American Journal of OphthalmologyPurpose: The purpose of the study was to evaluate changes in the ciliary body area (CBA) at rest and during accommodation in young patients, as measured by ultrabiomicroscopy (UBM).
Carlos Eduardo Rios-Elizondo +4 more
doaj +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To delineate specific in vivo white matter pathology in neuronal intranuclear inclusion disease (NIID) using diffusion spectrum imaging (DSI) and define its clinical relevance. Methods DSI was performed on 42 NIID patients and 38 matched controls.
Kaiyan Jiang +10 more
wiley +1 more source
Five‐Year Disease Progression in Synuclein Seeding Positive Sporadic Parkinson's Disease
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To provide a comprehensive description of disease progression in synuclein seeding assay (SAA) positive sporadic Parkinson Disease participants, using Neuronal Synuclein Disease integrated biological and functional impairment staging framework.
Paulina Gonzalez‐Latapi +19 more
wiley +1 more source
P3-1: Ophthalmologic Factors Influencing Asthenopia with Watching 3D Displays
i-Perception, 2012 Purpose: To identify ophthalmologic factors influencing asthenopia while watching 3D displays. Methods: 30 adult subjects without ophthalmologic abnormality watched the same 3D displays for 30 minutes.
Sungwook Wee, Namju Moon
doaj +1 more source