Results 91 to 100 of about 283,692 (299)
Changes in excitability and accommodation of human motor axons following brief periods of ischaemia. [PDF]
, 1991 1. The mechanism of post-ischaemic ectopic impulse generation in nerve is not known, and previous measurements of excitability changes in human motor axons have appeared to conflict.
Reid, G. +3 more
core +1 more source
Frontiers in Immunology, 2018 Cellular protection against undesired effects of complement activation is provided by expression of membrane-bound complement regulatory proteins including CD59.
Laura A. Michielsen +7 more
doaj +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Integrated fault estimation and accommodation design for discrete-time Takagi-Sugeno fuzzy systems with actuator faults [PDF]
, 2011 This paper addresses the problem of integrated robust fault estimation (FE) and accommodation for discrete-time Takagi–Sugeno (T–S) fuzzy systems. First, a multiconstrained reduced-order FE observer (RFEO) is proposed to achieve FE for discrete-time ...
Zhang, Ke +8 more
core +1 more source
FEBS Letters, EarlyView.The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
ORGINAL PAPER
Nott and MEM dynamic retinoscopy: Can they be used interchangeably?
Archives of Medical Science, 2006 Introduction: Previous studies suggest that monocular estimate method (MEM) and Nott retinoscopy yield identical results in the assessment of the accommodative lag.
Turki AlMubrad, Kelechi C. Ogbuehi
doaj