Epithelial–mesenchymal transition (EMT) and tumor‐infiltrating lymphocytes (TILs) are associated with early breast cancer response to neoadjuvant chemotherapy (NAC). This study evaluated EMT and TIL shifts, with immunofluorescence and RNA sequencing, at diagnosis and in residual tumors as potential biomarkers associated with treatment response.
Françoise Derouane+16 more
wiley +1 more source
ACCOMMODATION AND LOCAL RESPONSE IN MOTONEURONS OF TOAD'S SPINAL CORD
Tatsunosuke Araki, Takuzo Otani
openalex +2 more sources
The effect of temperature on the thermal conductivity and the accommodation coefficient of hydrogen [PDF]
Hamar Gregory
openalex +1 more source
Molecular and functional profiling unravels targetable vulnerabilities in colorectal cancer
We used whole exome and RNA‐sequencing to profile divergent genomic and transcriptomic landscapes of microsatellite stable (MSS) and microsatellite instable (MSI) colorectal cancer. Alterations were classified using a computational score for integrative cancer variant annotation and prioritization.
Efstathios‐Iason Vlachavas+15 more
wiley +1 more source
In 2004 a public private leasing arrangement, the Rental accommodation Scheme, was introduced into the housing system of the Republic of Ireland. Lauded as a more structured, accommodation-based approach to the use of the private rented sector to meet ...
Jordan, Mark
core
Peripheral blood proteome biomarkers distinguish immunosuppressive features of cancer progression
Immune status significantly influences cancer progression. This study used plasma proteomics to analyze benign 67NR and malignant 4T1 breast tumor models at early and late tumor stages. Immune‐related proteins–osteopontin (Spp1), lactotransferrin (Ltf), calreticulin (Calr) and peroxiredoxin 2 (Prdx2)–were associated with systemic myeloid‐derived ...
Yeon Ji Park+6 more
wiley +1 more source
Stochastic variation in the FOXM1 transcription program mediates replication stress tolerance
Cellular heterogeneity is a major cause of drug resistance in cancer. Segeren et al. used single‐cell transcriptomics to investigate gene expression events that correlate with sensitivity to the DNA‐damaging drugs gemcitabine and prexasertib. They show that dampened expression of transcription factor FOXM1 and its target genes protected cells against ...
Hendrika A. Segeren+4 more
wiley +1 more source
Piracy Accommodation and the Optimal Timing of Royalty Payments [PDF]
This paper generalizes the two-period model of Watt (2000) who demonstrates the possibility of optimal accommodation of a pirate when the royalty rate applying to a creation is uniform and second-period Cournot competition applies.
Alan E. Woodfield
core
Ueber verschiedene Veränderungen des Astigmatismus unter dem Einflusse der Accommodation [PDF]
W. Dobrowsky
openalex +1 more source
The exchange of energy between gas atoms and solid . II.—The temperature variation of the accommodation coefficient of helium [PDF]
John K. Roberts
openalex +1 more source