Results 61 to 70 of about 134,897 (267)
Canadian Journal for the Scholarship of Teaching and Learning, 2016 Increasing enrolments of post-secondary students with disabilities are resulting in accessibility services offices reaching capacity levels. This trend has created the ‘perfect storm’ in terms of meeting these students’ needs. While collaboration between
Laura Sokal
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Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Сравнительная политикаThe rise of China constitutes a challenge for the U.S. hegemonic aspirations. However, Washington reacts to it rather belatedly and with restrain. Up until the mid-2020s, the United States did not consider the preventive use of force as a means to deter ...
I. A. Istomin
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Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Frontiers in Energy Research, 2020 The new renewable portfolio standard policy issued by China on May 2019 stipulates a specific promotion scheme of a quota obligation mainly on power supply companies and power consumers to sell or buy an increasing proportion of their electricity from ...
Yinhe Bu +3 more
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Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Cromohs: Cyber Review of Modern HistoriographyAnalysing six-plus printed Jesuit narratives describing the conversion of Muslim (‘Turkish’ and ‘Moorish’) slaves in early modern Naples, this article considers the Jesuit use of publicity and diverse forms of accommodation, including the use of dreams ...
Justine Walden
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Optical Coherence Tomography Reveals Sigmoidal Crystalline Lens Changes during Accommodation
Vision, 2018 This study aimed to quantify biometric modifications of the anterior segment (AS) during accommodation and to compare them against changes in both accommodative demand and response.
George A. Gibson +3 more
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pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
Study Regarding the Tourism Sector in Romanian Economy [PDF]
Ovidius University Annals: Economic Sciences Series, 2021 The tourism sector is a driver for the socio-economic development of a country. According to World Travel & Tourism Council, the tourism sector contributes with 5,9% to the formation of Romania's GDP.
Maria Liliana Druiu
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