Results 101 to 110 of about 126,718 (310)
Вестник Волгоградского государственного университета. Серия 4. История, регионоведение, международные отношения, 2015 The article reviews the industrial restructuring of the Saratov region on a war footing at the beginning of the Great Patriotic War. The author shows some details of this process: the transfer of enterprises to produce defense products, accommodation and
Danilov Viktor Nikolaevich
doaj +1 more source
Beach fale tourism in Samoa: The value of indigenous ownership and control over tourism [PDF]
, 2009 This working paper reports on the findings of a research project which explores the budget tourism sector in Samoa as epitomized by beach fale tourism. Its main aim is to draw attention to the legitimacy and value of this often overlooked sector of the ...
Scheyvens, Regina
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Pathogenic Role of FGFR3 Autoantibodies in Small Fiber Neuropathy
Advanced Science, EarlyView.Autoantibodies against fibroblast growth factor receptor 3 (FGFR3) are identified as pathogenic drivers of pain in small fiber neuropathy. By binding to sensory neurons in dorsal root ganglia, FGFR3 autoantibodies activate MAPK signaling and induce hyperexcitability and mechanical hypersensitivity, establishing FGFR3 autoantibodies as a therapeutic ...
Lyuba Y. Salih +12 more
wiley +1 more source
The condition of the rural hospitality enterprises in rural tourism. The case of Serbia
Revista de la Facultad de Agronomía, 2018 Rural attractions has increasing opportunities to act as a basic resource for tourism, organised and sustained through locally owned small enterprises. Rural hospitality enterprises (RHEs) are a rapidly expanding and dynamic sector of the rural tourism ...
Aleksandra Vujko +2 more
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Versatile CRISPR‐Cas Tools for Gene Regulation in Zebrafish via an Enhanced Q Binary System
Advanced Science, EarlyView.This study introduces CRISPR‐Q, a transgenic CRISPR‐Cas system leveraging the QFvpr/QUAS binary expression platform in zebrafish. CRISPR‐Q overcomes previous challenges in achieving stable and efficient gene regulation. By enabling precise spatiotemporal control of transcript knockdown (CRISPR‐QKD) and gene activation (CRISPR‐Qa), it provides a ...
Miaoyuan Shi +13 more
wiley +1 more source
Discovery of H2 Receptor Antagonists as Colistin Enhancers by Targeting Acid Stress Response
Advanced Science, EarlyView.This study identifies YqgB as a key target for restoring colistin susceptibility in mcr‐positive pathogens under acidic conditions by remodeling phospholipid composition and reducing LPS modification. Deep learning‐based screening reveals H2 receptor antagonists as novel colistin adjuvants. Further investigations indicate that ranitidine and famotidine
Jinju Cai +7 more
wiley +1 more source
Cannington College: report from the Inspectorate (FEFC inspection report; 83/95 and 74/98) [PDF]
, 1998 Comprises two Further Education Funding Council (FEFC) inspection reports for the periods 1994-95 and 1997 ...
core
GPCRs in CAR‐T Cell Immunotherapy: Expanding the Target Landscape and Enhancing Therapeutic Efficacy
Advanced Science, EarlyView.Chimeric antigen receptor T cell therapy faces dual challenges of target scarcity and an immunosuppressive microenvironment in solid tumors. This review highlights how G protein‐coupled receptors can serve as both novel targets to expand the therapeutic scope and functional modules to enhance CAR‐T cell efficacy.
Zhuoqun Liu +11 more
wiley +1 more source
The "Customer Orientation" Principle – A Prerequisite for Increased Efficiency in Tourism [PDF]
Ovidius University Annals: Economic Sciences Series, 2018 In present, the tourism sector presents on a world scale, the most dynamic field of activity,tourism products and services, are constantly demanded by an increasing number of thepopulation, tourist attractiveness being a priority for the national economy.
Ștefan (Matei) Adriana
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TOURISM AS A WAY OF ECONOMIC DEVELOPMENT [PDF]
Tourism is one of the most complex industries of world and national economy. The income of tourism has a substantial direct or indirect influence on the other sectors while its performance depends on the condition of the environment.
Walter, Virag
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