Results 121 to 130 of about 4,193,458 (293)

Management accounting practices towards financial performance in manufacturing companies, Bangladesh: Mediating role of rationalized managerial decisions

open access: yesSocial Sciences and Humanities Open
The aim of this study is to analyze how management accounting practices affect the financial performance of manufacturing companies in Bangladesh, taking into account the potential influence of rationalized managerial decision-making.
Fahmida Begum, Md. Musfiqur Rahman
doaj   +1 more source

Indoleamine 2,3‐dioxygenase 1 inhibition reverses cancer‐associated fibroblast‐mediated immunosuppression in high‐grade serous ovarian cancer

open access: yesFEBS Open Bio, EarlyView.
CAF‐mediated immunosuppression in ovarian cancer is driven by IDO1, reducing T‐cell function. Inhibiting IDO1 restores T‐cell proliferation and cytotoxicity, increases cancer cell apoptosis, and may help overcome CAF‐induced immune suppression in high‐grade serous ovarian cancer. Targeting IDO1 may improve antitumor immunity.
Hyewon Lee   +3 more
wiley   +1 more source

THE BENEFITS OF ERP AND RPA INTEGRATION IN THE CONTEXT OF INDUSTRY 4.0: EFFICIENT MASTER DATA MANAGEMENT IN THE SAP SYSTEM [PDF]

open access: yesAnnals of the University of Craiova: Economic Sciences Series
Given the constant development of technology, the digitization of processes is a crucial issue for economic entities that want to increase performance.
Andreea Măldăreanu   +4 more
doaj  

A general model for analysis of linear and hyperbolic enzyme inhibition mechanisms

open access: yesFEBS Open Bio, EarlyView.
We developed a general enzyme kinetic model that integrates these six basic inhibition mechanism onto a single one. From this model, we deduced a general enzyme kinetic equation that through modulation of simple parameters, γ (the relative inhibitor affinity for two binding sites) and β (the reactivity of the enzyme–substrate–inhibitor complex), is ...
Rafael S. Chagas, Sandro R. Marana
wiley   +1 more source

ASSESSING THE DETERMINANTS OF PERFORMANCE IN WASTE RECYCLING COMPANIES IN THE CONTEXT OF INDUSTRY 4.0: AN ANALYTICAL APPROACH. [PDF]

open access: yesAnnals of the University of Craiova: Economic Sciences Series
This article analyzes the key factors that influence the performance of a production process in recycling plants as well as the unexpected results obtained by integrating advanced technologies.
Andreea Gabriela Tănase   +4 more
doaj  

Overview of molecular signatures of senescence and associated resources: pros and cons

open access: yesFEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas   +6 more
wiley   +1 more source

RPA SOLUTIONS: MANAGING ESSENTIAL TECHNOLOGIES FOR AUTOMATING ORGANIZATIONAL PROCESSES IN THE CONTEXT OF INDUSTRY 4.0 – A CASE STUDY [PDF]

open access: yesAnnals of the University of Craiova: Economic Sciences Series
Due to the rapid evolution of technology in recent years, the way in which everyday activities are approached is constantly changing. A multitude of innovative technologies based on artificial intelligence, various automation solutions such as software ...
Andreea Măldăreanu   +4 more
doaj  

Hands‐on protocol for preparing water‐soluble fractions from agri‐food samples for NMR‐based metabolomics analysis

open access: yesFEBS Open Bio, EarlyView.
This research protocol outlines a workflow for nuclear magnetic resonance (NMR)‐based metabolomics in the agri‐food sector. Using two case studies—strawberry leaves (solid matrix) and wine (liquid matrix)—it details the procedures for sample preparation, data acquisition, and processing.
Andrea Fernández‐Veloso   +4 more
wiley   +1 more source

DDX3X induces mesenchymal transition of endothelial cells by disrupting BMPR2 signaling

open access: yesFEBS Open Bio, EarlyView.
Elevated DDX3X expression led to downregulation of BMPR2, a key regulator of endothelial homeostasis and function. Our co‐immunoprecipitation assays further demonstrated a molecular interaction between DDX3X and BMPR2. Notably, DDX3X promoted lysosomal degradation of BMPR2, thereby impairing its downstream signaling and facilitating endothelial‐to ...
Yu Zhang   +7 more
wiley   +1 more source

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