Results 151 to 160 of about 387,146 (299)

The growth of planets by pebble accretion in evolving protoplanetary discs

, 2015
The formation of planets depends on the underlying protoplanetary disc structure, which in turn influences both the accretion and migration rates of embedded planets.
B. Bitsch, M. Lambrechts, A. Johansen
semanticscholar   +1 more source

Stochastic variation in the FOXM1 transcription program mediates replication stress tolerance

Molecular Oncology, EarlyView.
Cellular heterogeneity is a major cause of drug resistance in cancer. Segeren et al. used single‐cell transcriptomics to investigate gene expression events that correlate with sensitivity to the DNA‐damaging drugs gemcitabine and prexasertib. They show that dampened expression of transcription factor FOXM1 and its target genes protected cells against ...
Hendrika A. Segeren, Kathryn A. Wierenga, Frank M. Riemers, Elsbeth A. van Liere, Bart Westendorp   +4 more
wiley   +1 more source

The clinical spectrum of SMA‐PME and in vitro normalization of its cellular ceramide profile

Annals of Clinical and Translational Neurology, Volume 9, Issue 12, Page 1941-1952, December 2022., 2022
Abstract Objective The objectives of this study were to define the clinical and biochemical spectrum of spinal muscular atrophy with progressive myoclonic epilepsy (SMA‐PME) and to determine if aberrant cellular ceramide accumulation could be normalized by enzyme replacement.
Michelle M. Lee, Graeme S. V. McDowell, Darryl C. De Vivo, Daniel Friedman, Samuel F. Berkovic, Maria Spanou, Argirios Dinopoulos, Katheryn Grand, Pedro A. Sanchez‐Lara, Michelle Allen‐Sharpley, Jodi Warman‐Chardon, Alexander Solyom, Thierry Levade, Edward H. Schuchman, Steffany A. L. Bennett, David A. Dyment, Toni S. Pearson   +16 more
wiley   +1 more source

Analysis of coastal management strategies in responding to shoreline changes in Karimunjawa and Kemujan Islands of Central Java, Indonesia

Journal of Degraded and Mining Lands Management
The Karimunjawa National Park area has various coastal resources and ecosystems, such as mangrove forests, seagrass, and coral reefs, which provide a habitat for several vital organisms.
Suryanti Suryanti, Max Rudolf Muskananfola, Sigit Febrianto, Churun A'in   +3 more
doaj   +1 more source

Introduction by Terry Mayes to Part 1 of Littlejohn, A. (2003) Reusing Online Resources: Vision and Theoretical Perspectives

Journal of Interactive Media in Education, 2010
: Reading the five chapters in this part of the book has made me realize that, as is often the case with attitudes towards topics that are not often revisited, my view of learning objects was based on a simplified and rather crude version, based on ...
J. Terry Mayes
doaj   +1 more source

Plasma lipidomic and metabolomic profiles in high‐grade glioma patients before and after 72‐h presurgery water‐only fasting

Molecular Oncology, EarlyView.
Presurgery 72‐h fasting in GB patients leads to adaptations of plasma lipids and polar metabolites. Fasting reduces lysophosphatidylcholines and increases free fatty acids, shifts triglycerides toward long‐chain TGs and increases branched‐chain amino acids, alpha aminobutyric acid, and uric acid.
Iris Divé, Lisa Hahnefeld, Katharina J. Wenger, Donat Kögel, Joachim Steinbach, Gerd Geisslinger, Michael W. Ronellenfitsch, Irmgard Tegeder   +7 more
wiley   +1 more source

A transient inflammatory response contributes to oxaliplatin neurotoxicity in mice

Annals of Clinical and Translational Neurology, Volume 9, Issue 12, Page 1985-1998, December 2022., 2022
Abstract Objectives Peripheral neuropathy is a relevant dose‐limiting adverse event that can affect up to 90% of oncologic patients with colorectal cancer receiving oxaliplatin treatment. The severity of neurotoxicity often leads to dose reduction or even premature cessation of chemotherapy.
Aina Calls, Abel Torres‐Espin, Marc Tormo, Laura Martínez‐Escardó, Núria Bonet, Ferran Casals, Xavier Navarro, Víctor J. Yuste, Esther Udina, Jordi Bruna   +9 more
wiley   +1 more source

Evolution of Disk Accretion [PDF]

arXiv, 1999
We review the present knowledge of disk accretion in young low mass stars, and in particular, the mass accretion rate and its evolution with time. The methods used to obtain mass accretion rates from ultraviolet excesses and emission lines are described, and the current best estimates of mass accretion rate for Classical T Tauri stars and for objects ...
arxiv  

Relativistic Accretion [PDF]

, 1999
A brief summary of the properties of astrophysical black holes is presented. Various modes of accretion are distinguished, corresponding to accretion at rates from well below to well above the Eddington rate.
Blandford, Roger. D.
core   +2 more sources

Accretion Disc Particle Accretion in Major Merger Simulations

, 2013
A recent approach to simulating localized feedback from active galactic nuclei by Power et al. (2011) uses an accretion disc particle to represent both the black hole and its accretion disc.
Thacker, Rob J., Wurster, James
core   +1 more source