Results 41 to 50 of about 1,814 (268)
ACCRETION OUTBURSTS IN CIRCUMPLANETARY DISKS [PDF]
The Astrophysical Journal, 2012 We describe a model for the long term evolution of a circumplanetary disk that is fed mass from a circumstellar disk and contains regions of low turbulence (dead zones). We show that such disks can be subject to accretion driven outbursts, analogous to outbursts previously modeled in the context of circumstellar disks to explain FU Ori phenomena ...
Lubow, S. H., Martin, R. G.
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Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Molecular Oncology, EarlyView.Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano +6 more
wiley +1 more source
The Astrophysical JournalWe present the results of four 3D radiation magnetohydrodynamic simulations of accretion disks around a 10 ^8 solar mass black hole, which produce the far-ultraviolet spectrum peak and demonstrate a robust physical mechanism for producing the extreme ...
Yan-Fei Jiang +3 more
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Accretion-disk coronae in QSOs [PDF]
Publications of the Astronomical Society of the Pacific, 1991 Radiation pressure on gas in the hypothesized accretion disks of QSOs will result in a corona. Electrons of 340 kev, equivalent to Te∼3×108 K, may result in a significant. Compton optical depth for the implied mass loss rate. Comptonization of ultraviolet to 30 kev may result in contradiction to observations.
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Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
, 1995 49p. To appear in XXI Canary Islands Winter School of Astrophysics, ed. T. Shahbaz, CUP (significantly improved, expanded and updated version of an earlier text)
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Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens
FEBS Open Bio, EarlyView.Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee +3 more
wiley +1 more source
Evaluating the involvement of autolysosomes in the nuclear translocation of fluorescent proteins
FEBS Open Bio, EarlyView.Endogenously expressed fluorescent proteins can be degraded by autophagy and transported to cell nuclei via the nuclear pore complex. But in some cell lines, for example, HeLa cells which are positive for immunoreactivity of a receptor ligand, such as UCN I, in cell nuclei, fusion of autolysosome with the nuclear envelope is involved in the nuclear ...
Keiichi Ikeda
wiley +1 more source
The Evolution of Accreting Binaries: From Brown Dwarfs to Supermassive Black Holes
The Astrophysical JournalCircumbinary accretion occurs throughout the universe, from the formation of stars and planets to the aftermath of major galactic mergers. We present an extensive investigation of circumbinary accretion disks, studying circular binaries with mass ratios (
Alexander J. Dittmann, Geoffrey Ryan
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