Results 81 to 90 of about 229,036 (285)

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

FEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero, Maria Kopsida, Nathalie Arendt, Hans Lennernäs, Markus Sjöblom, Femke Heindryckx   +5 more
wiley   +1 more source

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

FEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour, Christine Volmert, Valentina Piano   +2 more
wiley   +1 more source

Time‐restricted feeding prior to Mycobacterium tuberculosis infection reduces tissue CD4+ T cells with limited impact on bacterial clearance

FEBS Open Bio, EarlyView.
Time‐restricted feeding (TRF) in mice increased liver fatty acid oxidation and decreased fatty acid biosynthesis. These alterations persisted when TRF was discontinued and the host was infected with Mycobacterium tuberculosis. Pre‐exposure to TRF did not alter tissue (lung and spleen) mycobacterial burden but significantly reduced CD3+ T cells in lungs
Ashish Gupta, Nidhi Yadav, Subhasmita Das, R. Rajendra Kumar Reddy, Nupur Sharma, Amol Ratnakar Suryawanshi, Jaswinder Singh Maras, Ranjan Kumar Nanda   +7 more
wiley   +1 more source

Research and analysis on factors influencing Beijing consumers' car purchase intention : taking BYD as an example

Independent Study (M.B.A. (International Business)) -- University of the Thai Chamber of Commerce, 2024In the booming fertile land of the Chinese automobile market, the wave of new energy vehicles is sweeping at an unprecedented speed, and its steady ...
Wu, Qiongyu
core   +1 more source

Development of an accumulation-based system for cost-effective chamber measurements of inert trace gas fluxes

, 2010
As soil–atmosphere fluxes of greenhouse gases are characterized by high temporal fluctuations, frequent measurements in the range of hours to days need to be deployed, resulting in high analytical costs.
S. K. Jones, Carter, Mette Sustmann, Albert, K.R., Carter, M.S., U. Skiba, Drewer, J., M. A. Sutton, P. Ambus, J. Drewer, Sutton, M.A., M. S. Carter, K. R. Albert, Albert, Kristian Rost, Jones, S.K., Ambus, P., Ambus, Per, Skiba, U.   +16 more
core   +1 more source

Estimates of repeatability and heritability of methane production in sheep using portable accumulation chambers

Animal Production Science, 2015
This study was designed to screen a large number of sheep to identify individuals with high and low methane (CH4) production, and to estimate repeatability and heritability of CH4 emissions in sheep, utilising portable accumulation chambers (PAC) designed for in-field use.
Goopy, John P., Robinson, D.L., Woodgate, R.T., Donaldson, A.J., Oddy, V.H., Vercoe, P.E., Hegarty, R.S.   +6 more
openaire   +2 more sources

Hydrostatic pressure activates HIF‐1α via β‐catenin to promote stemness in breast cancer cells

FEBS Open Bio, EarlyView.
To mimic the elevated intestinal fluid pressure in breast cancers, we loaded human breast cancer cells (MCF‐7, MDA‐MB‐453, and BT‐474) to 50 mmHg hydrostatic pressure. Hydrostatic pressure exposure upregulated HIF‐1α and induced stemness in MCF‐7 and BT‐474 cells.
Da Zhai, Yong Xu, Jingjing Ma, Ratchanee Duangrat, Chen Yan, Jingyan Liang, Hua Wei, Bin Jiang, Tao‐Sheng Li   +8 more
wiley   +1 more source

An automatic static chamber for continuous 220Rn and 222Rn flux measurements from soil

, 2004
A closed-circuit analytical system for the (quasi)-continuous measurement of radon fluxes from soil consisting of a static accumulation chamber and two radon detectors operated in series is described.
Lehmann, B.E., Salzmann, S., Conen, F., Ihly, B., Simon, E.   +4 more
core   +1 more source

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

FEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose, Kotaro Ozaki, Ryohei Kuriyama, Yuka Ikemoto, Kazuhiro Mio, Yuji C. Sasaki, Tatsuya Arai, Sakae Tsuda, Yoichi Shinkai, Masahiro Kuramochi   +9 more
wiley   +1 more source

Three-chamber bioelectrochemical system for biogas upgrading and nutrient recovery

, 2017
Here, an innovative three-chamber bioelectrochemical system configuration is proposed to combine COD, CO2 and NH4+ removal into a single device. In the proposed process, while COD oxidation and CO2 reduction occurred, respectively, in the anodic and ...
Zeppilli, Marco, M. Villano, Villano, Marianna, Majone, Mauro, Mattia, A., M. Zeppilli, A. Mattia, M. Majone   +7 more
core   +1 more source