Results 91 to 100 of about 8,276,674 (332)
ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
Molecular Oncology, EarlyView.We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source
Accuracy of smartwatches in predicting distance running performance
Frontiers in Sports and Active LivingObjectiveThis study examined the accuracy of smartwatches in predicting running performance.MethodsA total of 154 amateur runners (123 males and 31 females) were recruited. After wearing the HUAWEI WATCH GT Runner for a minimum of six weeks, the runners'
Jiansong Dai +4 more
doaj +1 more source
Monitoring Livestock Health by Modeling Rumination Behavior According to Accelerometer-Based Information [PDF]
Journal of Agricultural MachineryIntroductionThe livestock sector excels in the production of dairy and meat products. These products, serving as vital sources of animal protein, hold a significant position in household diets.
E. Vahedi Tekmehdash +4 more
doaj +1 more source
On the accuracy of thin-ice thickness retrieval using MODIS thermal imagery over Arctic first-year ice [PDF]
, 2013 Marko Mäkynen, Bin Cheng, M. Similä
openalex +1 more source
Thermistor connector assembly increases accuracy of measurements [PDF]
, 1965 Isolation of the thermistor from spurious heat transfer for accurately measuring ambient air temperatures is accomplished by a mounting consisting of a transparent plastic film bonded to a U-shaped phenolic board with depositions of aluminum on each face
core +1 more source
Molecular Oncology, EarlyView.This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris +10 more
wiley +1 more source
Communication: Molecular near-infrared transitions determined with sub-kHz accuracy [PDF]
, 2017 Jin Wang +4 more
openalex +1 more source
Sparsity-accuracy trade-off in MKL [PDF]
, 2009 We empirically investigate the best trade-off between sparse and uniformly-weighted multiple kernel learning (MKL) using the elastic-net regularization on real and simulated datasets.
Suzuki, Taiji, Tomioka, Ryota
core
Explicit model predictive control accuracy analysis
, 2015 Model Predictive Control (MPC) can efficiently control constrained systems in real-time applications. MPC feedback law for a linear system with linear inequality constraints can be explicitly computed off-line, which results in an off-line partition of ...
Di Cairano, Stefano +2 more
core +1 more source
Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source