Results 71 to 80 of about 5,019,202 (297)
Analysis of the dynamic state of the system "fixture – workpiece" [PDF]
Журнал інженерних наук, 2016 In this article the vibrations of the “fixture – workpiece” system arising during the cutting process at various manufacturing steps under machining of levers in different fixture systems were investigated by means of numerical simulation methods.V. О. Ivanov, V. E. Karpus, І. М. Dehtiarov, І. V. Pavlenko, Y. Rong +4 moredoaj Accuracy of a multiport network analyzer [PDF]
, 1995 The accuracy of a multiport vector network analyzer, which uses a new calibration concept, has been compared with a 2-port network analyzer that implements the classical TRL procedure.F. SAMPIETRO, L. BRUNETTI, A. FERRERO, Sanpietro, F., Ferrero, Andrea Pierenrico, Brunetti, L., F. SANPIETRO, Pisani, Umberto, BRUNETTI, LUCIANO, U. PISANI +9 morecore +1 more sourceTranslophagy—A potential link between autophagy impairment and translational errors
FEBS Letters, EarlyView.Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.Mykola V. Korolchuk, Gailing Ma, Robin Antrobus, Diego Manni, Marco Trevisan‐Herraz, Mustafa Khwaja, Max Brown, Gavin D. Richardson, Masaaki Komatsu, Daniel Erskine, Viktor I. Korolchuk, Tetsushi Kataura +11 morewiley +1 more sourcePreserving Accuracy in GenBank [PDF]
Science, 2008 GenBank, the public repository for nucleotide and protein sequences, is a critical resource for molecular biology, evolutionary biology, and ecology. While some attention has been drawn to sequence errors ([1][1]), common annotation errors also reduce the value of this database.Bruns, Thomas D., Blackwell, Meredith, Edwards, Ivan, Taylor, Andy F. S., Horton, Thomas, Zhang, Ning, Kõljalg, Urmas, May, Georgiana, Kuyper, Thomas W., Bever, James D., Gilbert, Gregory, Taylor, John W., DeSantis, Todd Z., Pringle, Anne, Borneman, James, Thorn, Greg, Berbee, Mary, Mueller, Gregory M., Andersen, Gary L., Vellinga, Else C., Branco, Sara, Anderson, Ian, Dickie, Ian A., Avis, Peter, Timonen, Sari, Kjøller, Rasmus, Lodge, D. J., Bateman, Richard M., Purvis, Andy, Crous, Pedro W., Hawkes, Christine, Barraclough, Tim, Burt, Austin, Nilsson, R. H., Larsson, Karl-Henrik, Alexander, Ian, Moncalvo, Jean-Marc, Berube, Jean, Spatafora, Joseph, Thorsten Lumbsch, H., Blair, Jaime E., Suh, Sung-Oui, Pfister, Donald H., Binder, Manfred, Boehm, Eric W., Kohn, Linda, Mata, Juan L., Dyer, Paul, Sung, Gi-Ho, Dentinger, Bryn, Simmons, Emory G., Baird, Richard E., Volk, Thomas J., Perry, Brian A., Kerrigan, Richard W., Campbell, Jinx, Rajesh, Jeewon, Reynolds, Don R., Geiser, David, Humber, Richard A., Hausmann, Natasha, Szaro, Tim, Stajich, Jason, Gathman, Allen, Peay, Kabir G., Henkel, Terry, Robinson, Clare H., Pukkila, Patricia J., Nguyen, Nhu H., Villalta, Christopher, Kennedy, Peter, Bergemann, Sarah, Catherine Aime, M., Kauff, Frank, Porras-Alfaro, Andrea, Gueidan, Cecile, Beck, Andreas, Andersen, Birgitte, Marek, Stephen, Crouch, Jo A., Kerrigan, Julia, Beagle Ristaino, Jean, Hodge, Kathie T., Kuldau, Gretchen, Samuels, Gary J., Raja, Huzefa A., Voglmayr, Hermann, Gardes, Monique, Janos, David P., Rogers, Jack D., Cannon, Paul, Woolfolk, Sandra W., Kistler, H. C., Castellano, Michael A., Maldonado-Ramírez, Sandra L., Kirk, Paul M., Farrar, James J., Osmundson, Todd, Currah, Randolph S., Vujanovic, Vladimir, Chen, Weidong, Korf, Richard P., Atallah, Zahi K., Harrison, Ken J., Guarro, Josep, Bates, Scott T., Enrico Bonello, Pierluigi, Bridge, Paul, Schell, Wiley, Rossi, Walter, Stenlid, Jan, Frisvad, Jens C., Miller, R. M., Baker, Scott E., Hallen, Heather E., Janso, Jeffrey E., Wilson, Andrew W., Conway, Kenneth E., Egerton-Warburton, Louise, Wang, Zheng, Eastburn, Darin, Ho, Wellcome W. Hong, Kroken, Scott, Stadler, Marc, Turgeon, Gillian, Lichtwardt, Robert W., Stewart, Elwin L., Wedin, Mats, Li, De-Wei, Uchida, Janice Y., Jumpponen, Ari, Deckert, Ron J., Beker, Henry J., Rogers, Scott O., Xu, Jianping, Johnston, Peter, Shoemaker, R. A., Liu, Miao, Marques, G., Summerell, Brett, Sokolski, Serge, Thrane, Ulf, Widden, Paul, Bruhn, Johann N., Bianchinotti, Virginia, Tuthill, Dorothy, Baroni, Timothy J., Barron, George, Hosaka, Kentaro, Jewell, Kelsea, Piepenbring, Meike, Sullivan, Raymond, Griffith, Gareth W., Bradley, S. G., Aoki, Takayuki, Yoder, Wendy T., Ju, Yu-Ming, Berch, Shannon M., Trappe, Matt, Duan, Weijun, Bonito, Gregory, Taber, Ruth A., Coelho, Gilberto, Bills, Gerald, Ganley, Austen, Agerer, Reinhard, Nagy, László, Roy, Barbara A., Læssøe, Thomas, Hallenberg, Nils, Tichy, Hans-Volker, Stalpers, Joost, Langer, Ewald, Scholler, Markus, Krueger, Dirk, Pacioni, Giovanni, Pöder, Reinhold, Pennanen, Taina, Capelari, Marina, Nakasone, Karen, Tewari, J. P., Miller, Andrew N., Decock, Cony, Huhndorf, Sabine, Wach, Mark, Vishniac, Helen S., Yohalem, David S., Smith, Matthew E., Glenn, Anthony E., Spiering, Martin, Lindner, Daniel L., Schoch, Conrad, Redhead, Scott A., Ivors, Kelly, Jeffers, Steven N., Geml, József, Okafor, Florence, Spiegel, Frederick W., Dewsbury, Damon, Carroll, Juliet, Pashley, Catherine, Taylor, D. L., Liles, Mark R., Cruse-Sanders, Jennifer, Fitzsimons, Michael, Hynson, Nicole +205 moreopenaire +4 more sourcesChiral separation of chloroalkanes with the chromatographic column onboard Martian rovers
FEBS Letters, EarlyView.Computer image of the Rosalind Franklin Rover of ESA's ExoMars mission. ExoMars is scheduled to land on planet Mars in Oxia Planum in 2029. This area represents an interesting spot to look for biosignatures. Investigations of ExoMars include measurement on molecular chirality. We show that chiral chloroalkanes, that have been identified on Mars, can be Asma Merzougui, Agnes Banreti, Armelle L. Ernst, Guillaume Leseigneur, Uwe J. Meierhenrich +4 morewiley +1 more sourceDevelopmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley +13 morewiley +1 more sourceA novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz +9 morewiley +1 more source