Results 61 to 70 of about 5,303,119 (298)

Preserving Accuracy in GenBank [PDF]

open access: yesScience, 2008
GenBank, the public repository for nucleotide and protein sequences, is a critical resource for molecular biology, evolutionary biology, and ecology. While some attention has been drawn to sequence errors ([1][1]), common annotation errors also reduce the value of this database.
Bruns, Thomas D.   +210 more
openaire   +4 more sources

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

open access: yesFEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux   +7 more
wiley   +1 more source

Analysis of the dynamic state of the system "fixture – workpiece" [PDF]

open access: yesЖурнал інженерних наук, 2016
In this article the vibrations of the “fixture – workpiece” system arising during the cutting process at various manufacturing steps under machining of levers in different fixture systems were investigated by means of numerical simulation methods.
V. О. Ivanov   +4 more
doaj  

Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy

open access: yesFEBS Letters, EarlyView.
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley   +1 more source

Judge-target trait similarity and accuracy: Does it 'take one to know one'? [PDF]

open access: yes, 2014
Accurate personality judgement has become increasingly important in the workplace, as research indicates that other-ratings of personality may be promising predictors of performance.
Sait, Zaakiyah
core   +1 more source

Flow Cytometry for Estimating Plant Genome Size: Revisiting Assumptions, Sources of Variation, Reference Standards, and Best Practices

open access: yesJournal of the American Society for Horticultural Science
Flow cytometry has been widely used to estimate relative and absolute genome sizes (DNA contents) of plants for more than 50 years. However, the accuracy of these estimates can vary widely because of many factors, including errors in the genome size ...
John Nix   +3 more
doaj   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Approximate Distributed Set Reconciliation with Defined Accuracy [PDF]

open access: yes, 2019
Mit aktuell vorhandenen Mitteln ist es schwierig, objektiv approximative Algorithmen zum Mengenabgleich gegenüberzustellen und zu vergleichen. Jeder Algorithmus kann durch unterschiedliche Wahl seiner jeweiligen Parameter an ein gegebenes Szenario ...
Kruber, Nico
core   +1 more source

Driver machine-tool adaptations and its technological capabilities [PDF]

open access: yesНаучно-технический вестник Брянского государственного университета, 2016
The article presents the design of the driver machine-tool adaptations based on rigid and floating center for machine tools of the turning group, as well as their technological capabilities in providing quality workpieces.
Erokhin V.V.
doaj  

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

open access: yesMolecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur   +11 more
wiley   +1 more source

Home - About - Disclaimer - Privacy