Results 61 to 70 of about 8,178,737 (285)
Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
Molecular Oncology, EarlyView.This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
wiley +1 more source
NanocompositesThis paper may be the first meta-analysis that presents a comprehensive synthesis of scientific works spanning the last five years, focusing on methodologies and results related to the analysis of nanocomposite using nanoparticles.
Rania Loukil +2 more
doaj +1 more source
Accuracy and Credal Imprecision [PDF]
, 2019 Many have claimed that epistemic rationality sometimes requires us to have imprecise credal states (i.e. credal states representable only by sets of credence functions) rather than precise ones (i.e.
Berger, Dominik, Das, Nilanjan
core +1 more source
Molecular Oncology, EarlyView.We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source
Tele Dentistry: An Advancement Tool in Dentistry [PDF]
Dental Journal of Advance StudiesBackground: The study documented below was conducted to highlight the accuracy of diagnosing caries in human teeth by examination of the intraoral photographs taken through the smartphone vs standard clinical examination through the dental operating ...
Navjot S Mann +4 more
doaj +1 more source
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
Molecular cancer prevention: Intercepting disease
Molecular Oncology, EarlyView.Oncological practice must evolve, from treating established tumours to proactive cancer interception before clinical manifestation. This will require mechanistic insight into tumour initiation, validated biomarkers of early disease development and redesigned clinical trials, enabling cancer interception to become a core pillar of oncology with the ...
Charlotte Grieco +2 more
wiley +1 more source
Overview of molecular signatures of senescence and associated resources: pros and cons
FEBS Open Bio, EarlyView.Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas +6 more
wiley +1 more source
Accuracy guarantees for L1-recovery
, 2010 We discuss two new methods of recovery of sparse signals from noisy observation based on $\ell_1$- minimization. They are closely related to the well-known techniques such as Lasso and Dantzig Selector.
Iouditski, Anatoli +1 more
core +4 more sources
On the accuracy of GAIA radial velocities [PDF]
, 2001 We have obtained 782 real spectra and used them as inputs for 6700 automatic cross-correlation runs to the aim of investigating the radial velocity accuracy that GAIA could potentially achieve as function of spectral resolution and signal-to-noise ratio.
Agnolin, P., Munari, U., Tomasella, L.
core +5 more sources