Results 151 to 160 of about 97,072 (276)

ACE2, the viral gateway [PDF]

Nature Medicine, 2020
openaire   +2 more sources

Effects of SARS-CoV-2 on the cardiovascular system: More issues to be addressed

Anatolian Journal of Cardiology, 2020
Yang Liu
doaj   +1 more source

Cardiac ACE2 expression.

, 2013
(A) ACE2 mRNA expression determined by real-time PCR, (B) Western blot for ACE2 in left ventricles and the signal densities quantified using ImageJ, (C) Representative images showing ACE2 staining in the left ventricles, in sham-operated and ...
Marina Lin (476967), Leanne Groban (360082), Zhuo Zhao (476965), Jaqueline Da Silva (476966), Jewell A. Jessup (360080), Mark C. Chappell (337543), Lindsay M. MacNamara (476968), Sarfaraz Ahmad (154725), Carlos M. Ferrario (154728), Hao Wang (39217)   +9 more
core   +1 more source

Sodium–glucose cotransporter 2 inhibitors for hypertension in cardiovascular–kidney–metabolic syndrome

Experimental Physiology, EarlyView.
Abstract The antihypertensive mechanism of sodium–glucose cotransporter 2 (SGLT2) inhibitors has been traditionally attributed to osmotic diuresis. However, emerging evidence reveals multifaceted mechanisms beyond diuresis, including regulation of the renin–angiotensin–aldosterone system, sympathetic nervous system suppression, ion homeostasis ...
Chunxiang Xu, Xingyu Qiu, Nan Xu, Gensheng Zhang, Enyin Lai, Liang Zhao   +5 more
wiley   +1 more source

Angiotensin‐converting enzyme and exercise adaptations: Genetic variability, pharmacological modulation and future directions

The Journal of Physiology, EarlyView.
Abstract figure legend ACE I/D genotype, enzyme activity and integrated physiological adaptations. Upper panel: Conceptual framework linking the ACE I/D polymorphism (left) with circulating/tissue ACE activity (centre; violin plots based on hypothetical data for illustration) and strength/power versus endurance phenotypes (right).
Tórur Sjúrðarson, Nikolai B. Nordsborg   +1 more
wiley   +1 more source

Computational modelling of cardiac fibroblast signalling reveals a key role for Ca2+ in driving atrial fibrillation‐associated fibrosis

The Journal of Physiology, EarlyView.
Abstract figure legend A pre‐existing fibroblast signalling model was enhanced by integrating atrial‐specific components and reactions linked to atrial fibrosis and atrial fibrillation (AF). The analysis highlights the central role of Ca2⁺ signalling in driving profibrotic responses to AF‐relevant stimuli, angiotensin‐II and transforming growth factor ...
Najme Khorasani, Haibo Ni, Jeffrey J Saucerman, Dobromir Dobrev, Stefano Morotti, Eleonora Grandi   +5 more
wiley   +1 more source

Plant‐Derived Probiotics From Fermented Foods: Current Evidence on Antiviral Mechanisms and Gut–Lung Axis Modulation

Food Frontiers, Volume 7, Issue 6, November 2026.
Plant‐derived probiotics from fermented foods exert anti‐respiratory virus effects via immune regulation, antiviral metabolites, and gut–lung axis, highlighting their advantages, key technologies, and application prospects. ABSTRACT Respiratory viral infections represent a major global public health threat, causing widespread morbidity, mortality, and ...
Yinghao Xing, Yaoyuan Hu, Yingying Ma, Peng Yao, Jingjing Jiang, Jiao Guo, Shuangmei Liu   +6 more
wiley   +1 more source

Covid‐19, ACE2 and the kidney [PDF]

Acta Physiologica, 2020
Hardenberg, Jan‐Hendrik B., Luft, Friedrich C.   +1 more
openaire   +2 more sources

Localization of Ace2 in yeast and hyphae.

, 2015
A) Fluorescence microscopy of strains ACE2-GFP NOP1-mCherry (OL2345), PMET3-ace2S-GFP NOP1-mCherry (OL2356), PMET3-ace2L-GFP NOP1-mCherry (OL2327) and NOP1-mCherry (OL2347) grown as yeasts.
Marie-Elisabeth Bougnoux (493284), Jaime Correa-Bordes (323498), Carlos R. Vázquez de Aldana (237032), Gavin Sherlock (827), Diana M. Calderón-Noreña (723903), Pilar Gutiérrez-Escribano (323494), Christophe d’Enfert (132308), Alberto González-Novo (723904), Encarnación Dueñas-Santero (723906), Sara Orellana-Muñoz (723905), Yolanda Arnáiz-Pita (237010), M. Belén Suárez (323495), Francisco del Rey (237025)   +12 more
core   +1 more source

Renin‐Angiotensin Signaling and Vascular Function: Insights into Health and Disease

Acta Physiologica, Volume 242, Issue 11, November 2026.
ABSTRACT The renin‐angiotensin system (RAS) is an essential regulator of vascular structure and function, and dysregulation of angiotensin II (Ang II) signaling plays a critical role in the development of hypertension and associated vascular complications.
Giovanni Bertoldi, Swapnil K. Sonkusare
wiley   +1 more source