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A Human β-Defensin-Based Recombinant Protein DF2-HSA Ameliorates Cytokine Storm [PDF]

open access: yesCells
Cytokine storm is a critical driver of acute respiratory distress syndrome and multiple organ failure. Human β-defensin 2 (HBD-2) is the first inducible defensin discovered in human body.
Yibo Du   +7 more
doaj   +2 more sources

Case Report: Cytokine storm syndrome causing retinal inflammatory factor storm [PDF]

open access: yesFrontiers in Immunology
Cytokine storm syndrome (CSS) represents a severe systemic inflammatory condition precipitated by the hyperactivation of immune cells and the consequent excessive release of cytokines, triggered by various factors.
Na Liu   +3 more
doaj   +2 more sources

Ebola Virus Binding to Tim-1 on T Lymphocytes Induces a Cytokine Storm.

open access: yesMBio, 2017
Ebola virus (EBOV) disease (EVD) results from an exacerbated immunological response that is highlighted by a burst in the production of inflammatory mediators known as a “cytokine storm.” Previous reports have suggested that nonspecific activation of T ...
Mathieu Iampietro   +2 more
exaly   +3 more sources

CXCL13 is a predictive biomarker in idiopathic multicentric Castleman disease

open access: yesNature Communications, 2022
Idiopathic multicentric Castleman disease (iMCD) is a life-threatening inflammatory disease requiring immediate intervention, for which the recommended first-line therapy is the Interleukin-6 pathway inhibitor siltuximab.
Sheila K. Pierson   +11 more
doaj   +1 more source

The lymph node transcriptome of unicentric and idiopathic multicentric Castleman disease

open access: yesHaematologica, 2022
Castleman disease is a polyclonal lymphoproliferative disorder characterized by unicentric or multicentric lymphadenopathy with characteristic histomorphological features, in addition to variable inflammatory symptomatology. The molecular mechanisms and
Pedro Horna   +4 more
doaj   +1 more source

Absence of “Cytokine Storm” in Hospitalized COVID-19 Patients: A Retrospective Cohort Study

open access: yesInfectious Disease Reports, 2021
Background: A rapidly growing number of publications cite “cytokine storm” as a contributing factor in coronavirus disease 2019 (COVID-19) pathology. However, a few recent reports led to questioning of “cytokine storm” theory in COVID-19.
Maeghan L. Ciampa   +6 more
doaj   +1 more source

Can Panax ginseng help control cytokine storm in COVID-19?

open access: yesJournal of Ginseng Research, 2022
Coronavirus disease 2019 (COVID-19) is currently a pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). COVID-19 are directly associated with hyper-activation of innate immune response that excessively produce pro-inflammatory
Jong Hee Choi   +5 more
doaj   +1 more source

Brain dysfunction in COVID‐19 and CAR‐T therapy: cytokine storm‐associated encephalopathy

open access: yesAnnals of Clinical and Translational Neurology, 2021
Objective Many neurological manifestations are associated with COVID‐19, including a distinct form of encephalopathy related to cytokine storm, the acute systemic inflammatory syndrome present in a subgroup of COVID‐19 patients.
Umberto Pensato   +7 more
doaj   +1 more source

Evolutionarily Conserved Long Non-coding RNA Regulates Gene Expression in Cytokine Storm During COVID-19

open access: yesFrontiers in Bioengineering and Biotechnology, 2021
Coronavirus is a family of viruses including alpha-, beta-, gamma-, delta-coronaviruses. Only alpha- and betacoronaviruses have been observed to infect humans.
Olanrewaju B. Morenikeji   +4 more
doaj   +1 more source

Baicalein self‐microemulsion based on drug–phospholipid complex for the alleviation of cytokine storm

open access: yesBioengineering & Translational Medicine, 2023
Cytokine storm is a phenomenon whereby the overreaction of the human immune system leads to the release of inflammatory cytokines, which can lead to multiple organ dysfunction syndrome.
Hengfeng Liao   +12 more
doaj   +1 more source

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