Results 31 to 40 of about 109,140 (300)
Calming the cytokine storm [PDF]
Nature Reviews Immunology, 2018 Two papers show that combining IL-1 blockade with chimeric antigen receptor T cell therapy for cancer can prevent the induction of a potentially lethal ‘cytokine storm’.
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Case Report: Tocilizumab for the Treatment of SARS-CoV-2 Infection in a Patient With Aplastic Anemia
Frontiers in Oncology, 2020 While cytokine storm develops in a minority of patients with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, novel treatment approaches are desperately needed for those in whom it does.
Gina Keiffer +5 more
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Respiratory Medicine Case Reports, 2021 It has been postulated that the underlying pathophysiology of COVID-19 is mediated by cytokine storm resulting in a hyperinflammatory state. A similar kind of cytokine-storm has been described in individuals undergoing veno-venous extracorporeal membrane
Kelsey Kaman +4 more
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Major predictive risk factors for а cytokine storm in COVID-19 patients (a retrospective clinical trials) [PDF]
Клиническая практика, 2021 Background: According to WHO, as of March 31, 2021, 127 877 462 confirmed cases of the new COVID-19 coronavirus infection were registered in the world, including 2 796 561 deaths (WHO Coronavirus Disease).
Anna Yu. Anisenkova +12 more
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Science-Business eXchange, 2010 U.S. and Brazilian researchers have found that SLIT2 can prevent tissue damage and death caused by the cytokine storm during bacterial sepsis or severe viral infections. Navigen Pharmaceuticals has licensed the findings and thinks the protein's enhancement of vascular stability could be more effective than strategies that target individual cytokines.
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Interferon lambdas: the next cytokine storm [PDF]
Gut, 2011 For two decades the scientific community has sought to understand why some people clear hepatitis C virus (HCV) and others do not. Recently, several large genome-wide association studies have identified single nucleotide polymorphisms (SNPs) linked to interferon lambda 3 (IFNλ3) that are associated with the spontaneous resolution and successful ...
Kelly, C, Klenerman, P, Barnes, E
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Chinese Medicine, 2021 Exaggerated immune response and cytokine storm are accounted for the severity of COVID-19, including organ dysfunction, especially progressive respiratory failure and generalized coagulopathy.
Yadong Fan +6 more
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Oncologic Emergencies: Immune-Based Cancer Therapies and Complications [PDF]
, 2020 Cancer therapies have undergone several recent advancements. Current cancer treatments include immune-based therapies comprised of checkpoint inhibitors, and adoptive immunotherapy; each treatment has the potential for complications that differ from ...
Brém, Elizabeth +2 more
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Enhancement of OVA-induced murine lung eosinophilia by co-exposure to contamination levels of LPS in Asian sand dust and heated dust. [PDF]
, 2014 BackgroundA previous study has shown that the aggravation of Asian sand dust (ASD) on ovalbumin (OVA)-induced lung eosinphilia was more severe in lipopolysaccharide (LPS)-rich ASD than in SiO2-rich ASD.
He, Miao +9 more
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Combination immunotherapy with anti-PD-L1 antibody and depletion of regulatory T cells during acute viral infections results in improved virus control but lethal immunopathology [PDF]
, 2020 Combination immunotherapy (CIT) is currently applied as a treatment for different cancers and is proposed as a cure strategy for chronic viral infections. Whether such therapies are efficient during an acute infection remains elusive.
Akhmetzyanova, Ilseyar [u.v.m.] +9 more
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