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As health systems worldwide grapple with the coronavirus disease-2019 (COVID-19) pandemic, patients with durable LVAD support represent a unique population at risk for the disease.
Vinh Q. Chau, MD +9 more
doaj +2 more sources
Dynamics of a cytokine storm. [PDF]
Six volunteers experienced severe inflammatory response during the Phase I clinical trial of a monoclonal antibody that was designed to stimulate a regulatory T cell response.
Hao Hong Yiu +2 more
doaj +4 more sources
Hemophagocytic lymphohistiocytosis (HLH) is a rare but life-threatening disease caused by excessive immune activation. Acquired HLH is seen in adults and is often caused by infection or malignancy.
Tiffany Y. Shaw MD, Michael Schivo MD
doaj +2 more sources
Coronavirus is a family of viruses including alpha-, beta-, gamma-, delta-coronaviruses. Only alpha- and betacoronaviruses have been observed to infect humans.
Olanrewaju B. Morenikeji +4 more
doaj +1 more source
Cytokine storm is a phenomenon whereby the overreaction of the human immune system leads to the release of inflammatory cytokines, which can lead to multiple organ dysfunction syndrome.
Hengfeng Liao +12 more
doaj +1 more source
Is Low Alveolar Type II Cell SOD3 in the Lungs of Elderly Linked to the Observed Severity of COVID-19? [PDF]
Human lungs single cell RNA sequencing data from healthy donors (elderly and young; GEO accession number GSE122960) were analyzed to isolate and specifically study gene expression in alveolar type II cells.
Abouhashem, Ahmed S. +3 more
core +1 more source
Cytokine Storms: Understanding COVID-19 [PDF]
The elevated circulating levels of cytokines associated with a variety of infectious and immune-mediated conditions are frequently termed a cytokine storm. Here, we explain the protective functions of cytokines in "ideal" responses; the multi-factorial origins that can drive these responses to become pathological; and how this ultimately leads to ...
Mangalmurti, Nilam +1 more
openaire +2 more sources
Association of Pregnancy With Coronavirus Cytokine Storm: Systematic Review and Meta-analysis
BackgroundCOVID-19 was first identified in Wuhan, China, in December 2019, spreading to the rest of the globe, becoming a pandemic.
John Muthuka +4 more
doaj +1 more source
Neurological manifestations and neuro-invasive mechanisms of the severe acute respiratory syndrome coronavirus type 2 [PDF]
Background and purpose Infections with coronaviruses are not always confined to the respiratory tract and various neurological manifestations have been reported.
Boon, Paul +6 more
core +2 more sources
Cytokine storm interference [PDF]
Viral infections are a natural and inevitable part of life. In healthy individuals, mortality increases when the body’s innate immune system quickly activates, creating a cytokine storm. A rapid and excessive release of cytokines into the bloodstream can cause acute respiratory distress syndrome and death.
openaire +1 more source

