Results 21 to 30 of about 109,140 (300)
Subduing the Inflammatory Cytokine Storm. [PDF]
The inflammatory cytokine response is essential for protective immunity, yet bacterial and viral pathogens often elicit an exaggerated response (“cytokine storm”) harmful to the host that can cause multi-organ damage and lethality. Much has been published recently on the cytokine storm within the context of the coronavirus pandemic, yet bacterial ...
Kaempfer R.
europepmc +3 more sources
A New Investigation into the Molecular Mechanism of Andrographolide towards Reducing Cytokine Storm
Cytokine storm is a condition in which the immune system produces an excessive number of inflammatory signals, which can result in organ failure and death.
Abdulaziz Alzahrani
doaj +1 more source
Virological aspects of Epstein-Barr virus infections. [PDF]
Epstein-Barr virus (EBV) is usually maintained in an asymptomatic and latent form by the host immune system, and primarily by EBV-specific cytotoxic T cells (CTLs).
Kimura, Hiroshi +2 more
core +1 more source
BackgroundThe newly identified betacoronavirus SARS-CoV-2 is the causative pathogen of the coronavirus disease of 2019 (COVID-19) that killed more than 3.5 million people till now.
Mohd Rehan +11 more
doaj +1 more source
CD28 between tolerance and autoimmunity: The side effects of animal models [version 1; referees: 2 approved] [PDF]
Regulation of immune responses is critical for ensuring pathogen clearance and for preventing reaction against self-antigens. Failure or breakdown of immunological tolerance results in autoimmunity.
A Aruffo +57 more
core +2 more sources
SARS-COV-2 protein NSP9 promotes cytokine production by targeting TBK1
SARS-COV-2 infection-induced excessive or uncontrolled cytokine storm may cause injury of host tissue or even death. However, the mechanism by which SARS-COV-2 causes the cytokine storm is unknown.
Yihua Zhang +8 more
doaj +1 more source
The Role of Cytokines and Chemokines in Severe Acute Respiratory Syndrome Coronavirus 2 Infections
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has resulted in countless infections and caused millions of deaths since its emergence in 2019.
Ren-Jun Hsu +10 more
doaj +1 more source
Although the etiopathogenesis of infections has been largely illuminated by technical and scientific developments in the past century; many issues are still not clear today. The word 'there is no disease, there is a patient' is stil valid today.
Mustafa Kurtuluş, Ibrahim Pirim
doaj +1 more source
Interference of the T cell and antigen-presenting cell costimulatory pathway using CTLA4-Ig (abatacept) prevents Staphylococcal enterotoxin B pathology [PDF]
Staphylococcal enterotoxin B (SEB) is a bacterial superantigen that binds the receptors in the APC/T cell synapse and causes increased proliferation of T cells and a cytokine storm syndrome in vivo.
Carter, Alun J +10 more
core +2 more sources
Cytokine Storm in the Novel Coronavirus Infection and Methods of its Correction
The aim of the study was to identify the role of cytokine storm in COVID-19, that emerged at the end of 2019, based on the analysis of 80 publications, including 17.4% Russian and 82.6% foreign publications for 2014–2020 with an average impact factor of ...
A. V. Ershov +3 more
doaj +1 more source

