Results 21 to 30 of about 76,784 (116)

Cytokine profiles in severe SARS-CoV-2 infection requiring extracorporeal membrane oxygenation support

open access: yesRespiratory Medicine Case Reports, 2021
It has been postulated that the underlying pathophysiology of COVID-19 is mediated by cytokine storm resulting in a hyperinflammatory state. A similar kind of cytokine-storm has been described in individuals undergoing veno-venous extracorporeal membrane
Kelsey Kaman   +4 more
doaj   +1 more source

Major predictive risk factors for а cytokine storm in COVID-19 patients (a retrospective clinical trials) [PDF]

open access: yesКлиническая практика, 2021
Background: According to WHO, as of March 31, 2021, 127 877 462 confirmed cases of the new COVID-19 coronavirus infection were registered in the world, including 2 796 561 deaths (WHO Coronavirus Disease).
Anna Yu. Anisenkova   +12 more
doaj   +1 more source

Natural products provide a new perspective for anti-complement treatment of severe COVID-19: a review

open access: yesChinese Medicine, 2021
Exaggerated immune response and cytokine storm are accounted for the severity of COVID-19, including organ dysfunction, especially progressive respiratory failure and generalized coagulopathy.
Yadong Fan   +6 more
doaj   +1 more source

Cytokine Storm as a Cellular Response to dsDNA Breaks: A New Proposal

open access: yesFrontiers in Immunology, 2021
Pathogenesis of cytokine storm is poorly understood. In this article we propose a new mechanism and suggest innovative therapeutic avenues for its prevention.
Snehal Shabrish, Indraneel Mittra
doaj   +1 more source

Clusterin expression and germinal center morphometry help distinguish idiopathic multicentric castleman disease from select lymphadenopathies

open access: yesFrontiers in Immunology
Idiopathic multicentric Castleman disease (iMCD) is a heterogeneous cytokine storm disorder involving systemic inflammation, multicentric lymphadenopathy with characteristic histopathology, and life-threatening multiple organ dysfunction.
Michael V. Gonzalez   +11 more
doaj   +1 more source

High Ferritin in a Critically ill COVID-19 Patient: The Calm before Cytokine Storm [PDF]

open access: yesJournal of Clinical and Diagnostic Research, 2020
Corona Virus Disease of 2019 (COVID-19) is spreading throughout the world and the United States with confirmed cases in all 50 states. Cytokine Release Syndrome (CRS), or cytokine storm, is being increasingly reported with severe cases of COVID-19 ...
Safa Saki , Mustafa Salam Mawih
doaj   +1 more source

Increase in Vascular Endothelial Growth Factor (VEGF) Expression and the Pathogenesis of iMCD-TAFRO

open access: yesBiomedicines
TAFRO (thrombocytopenia (T), anasarca (A), fever (F), reticulin fibrosis (F/R), renal failure (R), and organomegaly (O)) is a heterogeneous clinical subtype of idiopathic multicentric Castleman disease (iMCD) associated with a significantly poorer ...
Gordan Srkalovic   +3 more
doaj   +1 more source

Specialized pro-resolving lipid mediators regulate inflammatory macrophages: A paradigm shift from antibiotics to immunotherapy for mitigating COVID-19 pandemic

open access: yesFrontiers in Molecular Biosciences, 2023
The most severe clinical manifestations of the horrifying COVID-19 disease, that claimed millions of lives during the pandemic time, were Acute respiratory distress syndrome (ARDS), Coagulopathies, septic shock leading eventually to death.
Vikram Kumar   +10 more
doaj   +1 more source

Breast-implant associated unicentric castleman disease: a case report

open access: yesCurrent Problems in Cancer: Case Reports
ALK-negative anaplastic large cell lymphoma is a well-established hematologic complication of prosthetic breast implantation, but other rare conditions should also be considered.
Saishravan Shyamsundar   +12 more
doaj   +1 more source

The mechanistic basis linking cytokine storm to thrombosis in COVID-19

open access: yesThrombosis Update, 2022
It is now well established that infection with SARS-CoV-2 resulting in COVID-19 disease includes a severely symptomatic subset of patients in whom an aggressive and/or dysregulated host immune response leads to cytokine storm syndrome (CSS) that may be ...
Adam Wolf   +10 more
doaj   +1 more source

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