Results 21 to 30 of about 109,140 (300)

Subduing the Inflammatory Cytokine Storm. [PDF]

open access: yesInt J Mol Sci
The inflammatory cytokine response is essential for protective immunity, yet bacterial and viral pathogens often elicit an exaggerated response (“cytokine storm”) harmful to the host that can cause multi-organ damage and lethality. Much has been published recently on the cytokine storm within the context of the coronavirus pandemic, yet bacterial ...
Kaempfer R.
europepmc   +3 more sources

A New Investigation into the Molecular Mechanism of Andrographolide towards Reducing Cytokine Storm

open access: yesMolecules, 2022
Cytokine storm is a condition in which the immune system produces an excessive number of inflammatory signals, which can result in organ failure and death.
Abdulaziz Alzahrani
doaj   +1 more source

Virological aspects of Epstein-Barr virus infections. [PDF]

open access: yes, 2005
Epstein-Barr virus (EBV) is usually maintained in an asymptomatic and latent form by the host immune system, and primarily by EBV-specific cytotoxic T cells (CTLs).
Kimura, Hiroshi   +2 more
core   +1 more source

A Computational Approach Identified Andrographolide as a Potential Drug for Suppressing COVID-19-Induced Cytokine Storm

open access: yesFrontiers in Immunology, 2021
BackgroundThe newly identified betacoronavirus SARS-CoV-2 is the causative pathogen of the coronavirus disease of 2019 (COVID-19) that killed more than 3.5 million people till now.
Mohd Rehan   +11 more
doaj   +1 more source

CD28 between tolerance and autoimmunity: The side effects of animal models [version 1; referees: 2 approved] [PDF]

open access: yes, 2018
Regulation of immune responses is critical for ensuring pathogen clearance and for preventing reaction against self-antigens. Failure or breakdown of immunological tolerance results in autoimmunity.
A Aruffo   +57 more
core   +2 more sources

SARS-COV-2 protein NSP9 promotes cytokine production by targeting TBK1

open access: yesFrontiers in Immunology, 2023
SARS-COV-2 infection-induced excessive or uncontrolled cytokine storm may cause injury of host tissue or even death. However, the mechanism by which SARS-COV-2 causes the cytokine storm is unknown.
Yihua Zhang   +8 more
doaj   +1 more source

The Role of Cytokines and Chemokines in Severe Acute Respiratory Syndrome Coronavirus 2 Infections

open access: yesFrontiers in Immunology, 2022
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has resulted in countless infections and caused millions of deaths since its emergence in 2019.
Ren-Jun Hsu   +10 more
doaj   +1 more source

COVID-19 and Cytokine Storm

open access: yesForbes Tıp Dergisi, 2020
Although the etiopathogenesis of infections has been largely illuminated by technical and scientific developments in the past century; many issues are still not clear today. The word 'there is no disease, there is a patient' is stil valid today.
Mustafa Kurtuluş, Ibrahim Pirim
doaj   +1 more source

Interference of the T cell and antigen-presenting cell costimulatory pathway using CTLA4-Ig (abatacept) prevents Staphylococcal enterotoxin B pathology [PDF]

open access: yes, 2017
Staphylococcal enterotoxin B (SEB) is a bacterial superantigen that binds the receptors in the APC/T cell synapse and causes increased proliferation of T cells and a cytokine storm syndrome in vivo.
Carter, Alun J   +10 more
core   +2 more sources

Cytokine Storm in the Novel Coronavirus Infection and Methods of its Correction

open access: yesАнтибиотики и Химиотерапия, 2021
The aim of the study was to identify the role of cytokine storm in COVID-19, that emerged at the end of 2019, based on the analysis of 80 publications, including 17.4% Russian and 82.6% foreign publications for 2014–2020 with an average impact factor of ...
A. V. Ershov   +3 more
doaj   +1 more source

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