Results 181 to 190 of about 149,286 (348)

Structure of the SARS-CoV-2 spike receptor-binding domain bound to the ACE2 receptor

Nature, 2020
J. Lan, J. Ge, Jinfang Yu, S. Shan, Huan Zhou, S. Fan, Qi Zhang, Xuanling Shi, Qisheng Wang, Linqi Zhang, Xinquan Wang   +10 more
semanticscholar   +1 more source

Two causes of COVID‐19‐related myocardial injury‐associated cardiogenic shock: Myocarditis and microvascular thrombosis

ESC Heart Failure, Volume 12, Issue 2, Page 1514-1522, April 2025.
Takamasa Iwai, Hirohiko Aikawa, Yoshiaki Morita, Keiko Ohta‐Ogo, Teruo Noguchi   +4 more
wiley   +1 more source

The fc fragment of IgMs binds C1q to activate the first step of the classical complement pathway, while inhibiting complement‐dependent cytotoxicity

The FEBS Journal, EarlyView.
Multimeric IgM‐fragment crystallizable region (Fc) fragments retain the ability to bind C1q and initiate the classical complement pathway, leading to C4 activation and deposition in vitro. However, the Fc cores can also inhibit complement‐dependent cytotoxicity by competing with surface‐bound antibodies for C1q engagement.
Andrea J. Pinto, Anne Chouquet, Isabelle Bally, Véronique Rossi, Nicole M. Thielens, Chantal Dumestre‐Pérard, Renate Kunert, Christine Gaboriaud, Wai Li Ling, Jean‐Baptiste Reiser   +9 more
wiley   +1 more source

SARS-CoV-2 Cell Entry Depends on ACE2 and TMPRSS2 and Is Blocked by a Clinically Proven Protease Inhibitor

Cell, 2020
M. Hoffmann, Hannah Kleine-Weber, S. Schroeder, Nadine Krüger, T. Herrler, Sandra Erichsen, T. Schiergens, G. Herrler, N. Wu, A. Nitsche, M. Müller, C. Drosten, S. Pöhlmann   +12 more
semanticscholar   +1 more source

Combined use of the hepatitis C drugs and amentoflavone could interfere with binding of the spike glycoprotein of SARS-CoV-2 to ACE2: the results of a molecular simulation study

, 2021
Kateryna V. Miroshnychenko, Anna V. Shestopalova   +1 more
openalex   +2 more sources

Humoral epitope dominance and immune imprinting by SARS‐CoV‐1 and SARS‐CoV‐2 vaccines

Immunology &Cell Biology, EarlyView.
We investigated Modified Vaccinia Ankara (MVA) vaccine candidates expressing the SARS‐CoV‐1 or SARS‐CoV‐2 Spike, as a primary or booster immunization, for their ability to induce antibodies targeting different epitopes on the SARS‐CoV‐2 RBD and broad cross‐reactive or cross‐neutralizing responses in C57BL/6 and antibody humanized (Ig‐humanized) mice ...
Deborah L Burnett, Ania Moxon, Anupriya Aggarwal, Katherine JL Jackson, Catherine Cotter, Anouschka Akerman, Amanda Russell, Rachel Kalman, David Langley, Jake Y Henry, Daniel Christ, Rowena A Bull, Robert Brink, Anthony D Kelleher, Hans‐Martin Jäck, Stuart Turville, Bernard Moss, Christopher C Goodnow   +17 more
wiley   +1 more source

Correction to "Controlled Hemorrhage Sensitizes Angiotensin II-Elicited Hypertension Through Activation of the Brain Renin-Angiotensin System Independently of Endoplasmic Reticulum Stress". [PDF]

Oxid Med Cell Longev
Oxidative Medicine and Cellular Longevity, Volume 2026, Issue 1, 2026.
europepmc   +2 more sources

COVID‐19 and vertical transmission: assessing the expression of ACE2/TMPRSS2 in the human fetus and placenta to assess the risk of SARS‐CoV‐2 infection [PDF]

, 2021
Max Arran Beesley, JR Davidson, Francesco Panariello, Soichi Shibuya, Dominic Scaglioni, Brendan C. Jones, Kasia Maksym, Oluwaseun Ogunbiyi, Neil J. Sebire, Davide Cacchiarelli, Anna L. David, Paolo De Coppi, M Gerli   +12 more
openalex   +1 more source

Mass‐Standardised Differential Antibody Binding to a Spectrum of SARS‐CoV‐2 Variant Spike Proteins: Wuhan, Alpha, Beta, Gamma, Delta, Omicron BA.1, BA.4/5, BA.2.75 and BA.2.12.1 Variants—Antibody Immunity Endotypes

Immunology, EarlyView.
Fully quantitative, mass‐standardised, antibody responses to ten SARS‐CoV‐2 variants show significant variation in immunity profiles or endotypes. The incidence of the complete response to all variants is significantly improved after three vaccinations.
Philip H. James‐Pemberton, Shivali Kohli, Jordan Twynham, Aaron C. Westlake, Alex Antill, Rouslan V. Olkhov, Andrew M. Shaw   +6 more
wiley   +1 more source

ACE2 downregulation in olfactory mucosa: Eosinophilic rhinosinusitis as COVID‐19 protective factor? [PDF]

, 2021
Concepció Marı́n, Valeria Tubita, Cristóbal Langdon, Mireya Fuentes, María Jesús Rojas‐Lechuga, Antonio Valero, Isam Alobid, Joaquim Mullol   +7 more
openalex   +1 more source